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  • Orr, Nick (author)

Genome-wide association study identifies a common variant in RAD51B associated with male breast cancer risk

  • Article/chapterEnglish2012

Publisher, publication year, extent ...

  • 2012-09-23
  • Springer Science and Business Media LLC,2012

Numbers

  • LIBRIS-ID:oai:lup.lub.lu.se:72773106-a12e-4cbb-8a5e-550403775f69
  • https://lup.lub.lu.se/record/3283699URI
  • https://doi.org/10.1038/ng.2417DOI

Supplementary language notes

  • Language:English
  • Summary in:English

Part of subdatabase

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  • Subject category:art swepub-publicationtype
  • Subject category:ref swepub-contenttype

Notes

  • We conducted a genome-wide association study of male breast cancer comprising 823 cases and 2,795 controls of European ancestry, with validation in independent sample sets totaling 438 cases and 474 controls. A SNP in RAD51B at 14q24.1 was significantly associated with male breast cancer risk (P = 3.02 x 10(-13); odds ratio (OR) = 1.57). We also refine association at 16q12.1 to a SNP within TOX3 (P = 3.87 x 10(-15); OR = 1.50).

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Lemnrau, Alina (author)
  • Cooke, Rosie (author)
  • Fletcher, Olivia (author)
  • Tomczyk, Katarzyna (author)
  • Jones, Michael (author)
  • Johnson, Nichola (author)
  • Lord, Christopher J. (author)
  • Mitsopoulos, Costas (author)
  • Zvelebil, Marketa (author)
  • McDade, Simon S. (author)
  • Buck, Gemma (author)
  • Blancher, Christine (author)
  • Trainer, Alison H. (author)
  • James, Paul A. (author)
  • Bojesen, Stig E. (author)
  • Bokmand, Susanne (author)
  • Nevanlinna, Heli (author)
  • Mattson, Johanna (author)
  • Friedman, Eitan (author)
  • Laitman, Yael (author)
  • Palli, Domenico (author)
  • Masala, Giovanna (author)
  • Zanna, Ines (author)
  • Ottini, Laura (author)
  • Giannini, Giuseppe (author)
  • Hollestelle, Antoinette (author)
  • van den Ouweland, Ans M. W. (author)
  • Novakovic, Srdjan (author)
  • Krajc, Mateja (author)
  • Gago-Dominguez, Manuela (author)
  • Castelao, Jose Esteban (author)
  • Olsson, HåkanLund University,Lunds universitet,Bröstcancer-genetik,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Breastcancer-genetics,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)onk-hol (author)
  • Hedenfalk, IngridLund University,Lunds universitet,Bröstcancer-genetik,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Bröst- och ovarialcancer,Forskargrupper vid Lunds universitet,Breastcancer-genetics,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine,Breast and Ovarian Cancer Genomics,Lund University Research Groups(Swepub:lu)onk-ifa (author)
  • Easton, Douglas F. (author)
  • Pharoah, Paul D. P. (author)
  • Dunning, Alison M. (author)
  • Bishop, D. Timothy (author)
  • Neuhausen, Susan L. (author)
  • Steele, Linda (author)
  • Houlston, Richard S. (author)
  • Garcia-Closas, Montserrat (author)
  • Ashworth, Alan (author)
  • Swerdlow, Anthony J. (author)
  • Bröstcancer-genetikSektion I (creator_code:org_t)

Related titles

  • In:Nature Genetics: Springer Science and Business Media LLC44:11, s. 1182-11841546-17181061-4036

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