Search: WFRF:(Järås J.) >
Sol-gel integrated ...
Sol-gel integrated protein microarray for high-resolution signal readout of psa (prostate specific antigen) in clinical samples
-
- Lee, S. W. (author)
- Lund University,Lunds universitet,Avdelningen för Biomedicinsk teknik,Institutionen för biomedicinsk teknik,Institutioner vid LTH,Lunds Tekniska Högskola,Department of Biomedical Engineering,Departments at LTH,Faculty of Engineering, LTH
-
- Ahn, J. Y. (author)
- Dongguk University, Seoul
-
- Järås, K. (author)
- Lund University,Lunds universitet,Avdelningen för Biomedicinsk teknik,Institutionen för biomedicinsk teknik,Institutioner vid LTH,Lunds Tekniska Högskola,Klinisk kemi, Malmö,Forskargrupper vid Lunds universitet,Department of Biomedical Engineering,Departments at LTH,Faculty of Engineering, LTH,Clinical Chemistry, Malmö,Lund University Research Groups
-
show more...
-
- Lilja, H. (author)
- Lund University,Lunds universitet,Klinisk kemi, Malmö,Forskargrupper vid Lunds universitet,Clinical Chemistry, Malmö,Lund University Research Groups
-
- Jo, M. J. (author)
- Dongguk University, Seoul
-
- Jung, C. Y. (author)
- Dongguk University, Seoul
-
- Jeong, O. C. (author)
- Inje University
-
- Kim, S. Y. (author)
- Dongguk University, Seoul
-
- Laurell, T. (author)
- Lund University,Lunds universitet
-
show less...
-
(creator_code:org_t)
- 2010
- 2010
- English.
-
In: 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010. - 9781618390622 ; 2, s. 800-802
- Related links:
-
https://lup.lub.lu.s...
Abstract
Subject headings
Close
- In this study, we demonstrate a new protein microarray technology for highly sensitive detection of PSA (prostate caser specific antigen) in scrum samples. Using the optically active sol-gel nanocomposites, which can hold capturing probes in native and surface morphology tailored porous silicon, purified PSA (Prostate Specific Antigen) in human female serum was assessed by FlTC-antiPSA in broad dynamic range of the sandwich (1 pg/mL to Ing/mL). Additionally, we tested reverse phase assay using our developed system, which purified PSA imbedded in sol-gel and FITC labeled its counter antibody was accessed. Dynamic range was 60 fg/mL to 6ng/mL. Our concept can allow the measurement oflow amount of PSA at pg/ml range and thus, it is possible to do relative quantification for marker protein as well.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Läkemedelskemi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Medicinal Chemistry (hsv//eng)
Keyword
- Porous silicon
- Sol-gel microarray. PSA
Publication and Content Type
- kon (subject category)
- ref (subject category)
Find in a library
To the university's database