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Importance of facto...
Importance of factors determining the low health-related quality of life in people presenting with a diabetic foot ulcer: the Eurodialestudy
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Siersma, V. (author)
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Thorsen, H. (author)
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Holstein, P. E. (author)
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Kars, M. (author)
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- Apelqvist, Jan (author)
- Lund University,Lunds universitet,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Genomics, Diabetes and Endocrinology,Lund University Research Groups
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Jude, E. B. (author)
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Piaggesi, A. (author)
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Bakker, K. (author)
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Edmonds, M. (author)
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Jirkovska, A. (author)
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Mauricio, D. (author)
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Tennvall, G. Ragnarson (author)
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Reike, H. (author)
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Spraul, M. (author)
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Uccioli, L. (author)
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Urbancic, V. (author)
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van Acker, K. (author)
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van Baal, J. (author)
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Schaper, N. C. (author)
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(creator_code:org_t)
- 2013-07-15
- 2013
- English.
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In: Diabetic Medicine. - : Wiley. - 1464-5491 .- 0742-3071. ; 30:11, s. 1382-1387
- Related links:
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http://dx.doi.org/10...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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Abstract
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- AimTo identify the factors responsible for the low health-related quality of life associated with foot ulcers and the relative importance of these factors. MethodsA total of 1232 patients with a new foot ulcer, who presented at one of the 14 centres in 10 European countries participating in the Eurodiale study, were included in this cross-sectional study. Patient and ulcer characteristics were obtained as well as results from the Euro-Qol-5D questionnaire, a health-related quality of life instrument with five domains (mobility, self-care, usual activities, pain/discomfort and anxiety/depression). To analyse the relative importance of comorbidities and ulcer- and patient-related factors for health-related quality of life, linear regression models were used to calculate the relative contributions of each factor to the fit (R-2) of the model. ResultsPatients reported poor overall health-related quality of life, with problems primarily in the mobility and pain/discomfort domains. Among the comorbidities, the inability to stand or walk without help was the most important determinant of decreased health-related quality of life in all five domains. Among ulcer-related factors, ulcer size, limb-threatening ischaemia and elevated C-reactive protein concentration also had high importance in all domains. The clinical diagnosis of infection, peripheral arterial disease and polyneuropathy were only important in the pain/discomfort domain. ConclusionsThe factors that determine health-related quality of life are diverse and to an extent not disease-specific. To improve health-related quality of life, treatment should not only be focused on ulcer healing but a multifactorial approach by a specialized multidisciplinary team is also important. What's new? The inability to stand or walk without help is the most important determinant of poor health-related quality of life. Other factors with high importance are ulcer size, elevated C-reactive protein concentration and limb-threatening ischaemia. To improve health-related quality of life, treatment should not only be focused on ulcer healing but a multifactorial approach by a specialized multidisciplinary team is also important.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Endokrinologi och diabetes (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Endocrinology and Diabetes (hsv//eng)
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- art (subject category)
- ref (subject category)
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- By the author/editor
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Siersma, V.
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Thorsen, H.
-
Holstein, P. E.
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Kars, M.
-
Apelqvist, Jan
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Jude, E. B.
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show more...
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Piaggesi, A.
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Bakker, K.
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Edmonds, M.
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Jirkovska, A.
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Mauricio, D.
-
Tennvall, G. Rag ...
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Reike, H.
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Spraul, M.
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Uccioli, L.
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Urbancic, V.
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van Acker, K.
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van Baal, J.
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Schaper, N. C.
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Endocrinology an ...
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Diabetic Medicin ...
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Lund University