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L773:0002 953X
 

Sökning: L773:0002 953X > Lunds universitet > Soderstrom H > The serotonin syste...

  • Borg, JacquelineKarolinska Institutet (författare)

The serotonin system and spiritual experiences

  • Artikel/kapitelEngelska2003

Förlag, utgivningsår, omfång ...

  • American Psychiatric Association Publishing,2003

Nummerbeteckningar

  • LIBRIS-ID:oai:lup.lub.lu.se:784041d6-f8d9-4f30-85ae-2a3fee0e953b
  • https://lup.lub.lu.se/record/1126647URI
  • https://doi.org/10.1176/appi.ajp.160.11.1965DOI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:1951583URI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

Ingår i deldatabas

Klassifikation

  • Ämneskategori:art swepub-publicationtype
  • Ämneskategori:ref swepub-contenttype

Anmärkningar

  • OBJECTIVE: The serotonin system has long been of interest in biological models of human personality. The purpose of this positron emission tomography (PET) study was to search for relationships between serotonin 5-HT(1A) receptor density and personality traits. METHOD: Fifteen normal male subjects, ages 20-45 years, were examined with PET and the radioligand [(11)C]WAY100635. Personality traits were assessed with the Swedish version of the Temperament and Character Inventory self-report questionnaire. Binding potential, an index for the density of available 5-HT(1A) receptors, was calculated for the dorsal raphe nuclei, the hippocampal formation, and the neocortex. For each region, correlation coefficients between 5-HT(1A) receptor binding potential and Temperament and Character Inventory personality dimensions were calculated and analyzed in two-tailed tests for significance. RESULTS: The authors found that the binding potential correlated inversely with scores for self-transcendence, a personality trait covering religious behavior and attitudes. No correlations were found for any of the other six Temperament and Character Inventory dimensions. The self-transcendence dimension consists of three distinct subscales, and further analysis showed that the subscale for spiritual acceptance correlated significantly with binding potential but not with the other two subscales. CONCLUSIONS: This finding in normal male subjects indicated that the serotonin system may serve as a biological basis for spiritual experiences. The authors speculated that the several-fold variability in 5-HT(1A) receptor density may explain why people vary greatly in spiritual zeal.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Andree, Bengt (författare)
  • Anckarsäter, HenrikLund University,Lunds universitet,Rättspsykiatri, Malmö,Forskargrupper vid Lunds universitet,Forensic Psychiatry, Malmö,Lund University Research Groups(Swepub:lu)med-hka (författare)
  • Farde, LarsKarolinska Institutet (författare)
  • Soderstrom, H (författare)
  • Karolinska InstitutetRättspsykiatri, Malmö (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:American Journal of Psychiatry: American Psychiatric Association Publishing160:11, s. 1965-19691535-72280002-953X

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