Non-functioning pituitary microadenoma in children and adolescents : Is follow-up with diagnostic imaging necessary?

↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Search: WFRF:(Erfurth Eva Marie) > (2020-2023) > Non-functioning pit...

Details
MARC

Borghammar, CamillaLund University,Lunds universitet,Pediatrik, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Paediatrics (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital (author)

Non-functioning pituitary microadenoma in children and adolescents : Is follow-up with diagnostic imaging necessary?

Article/chapterEnglish2023

Publisher, publication year, extent ...

2022-10-17
Springer Science and Business Media LLC,2023

Numbers

LIBRIS-ID:oai:lup.lub.lu.se:7e685571-b99f-4319-8daa-a46cd6f9dbaa
https://lup.lub.lu.se/record/7e685571-b99f-4319-8daa-a46cd6f9dbaaURI
https://doi.org/10.1007/s12020-022-03212-7DOI

Supplementary language notes

Language:English
Summary in:English

Part of subdatabase

SwePubSwePub

Classification

Subject category:art swepub-publicationtype
Subject category:ref swepub-contenttype

Notes

PURPOSE: No consensus exists regarding follow-up recommendations for suspected pituitary microadenoma in children. To address this knowledge gap, we investigated the growth potential of pituitary solid and cystic lesions <10 mm in children and evaluated the accuracy of magnetic resonance imaging (MRI) measurements.METHODS: The children included were <18 years at first pituitary MRI and radiologically diagnosed with a non-functioning microadenoma or cyst <10 mm. Lesion size at first and latest MRI as well as all individual MRI examinations were re-evaluated.RESULTS: In total, 74 children, median age 12 years (range 3-17), had a non-functioning microadenoma, probable microadenoma, or cyst. Of these, 55 underwent repeated MRI (median 3, range 2-7) with a median follow-up of 37 months (range 4-189). None of the pituitary lesions without hormonal disturbances increased significantly during follow-up. Two radiologists agreed that no lesion could be identified in 38/269 (14%) MRI examinations, and in 51/231 (22%) they disagreed about lesion location. In 34/460 (7%) MRI measurements size differed >2 mm, which had been considered significant progression.CONCLUSION: Non-functioning pituitary microadenoma in children has small size variations, often below the spatial resolution of the scanners. We suggest lesions <4 mm only for clinical follow-up, lesions 4-6 mm for MRI after 2 years and ≥7 mm MRI after 1 and 3 years, with clinical follow-up in between. If no progression, further MRI should only be performed after new clinical symptoms or hormonal disturbances.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

Tamaddon, AshkanLund University,Lunds universitet,Diagnostisk radiologi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Diagnostic Radiology, (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital(Swepub:lu)as2852ta (author)
Erfurth, Eva-MarieLund University,Lunds universitet,Endokrin,Forskargrupper vid Lunds universitet,Endocrine,Lund University Research Groups,Skåne University Hospital(Swepub:lu)med-ee0 (author)
Sundgren, Pia CLund University,Lunds universitet,Lund University Bioimaging Center,Medicinska fakulteten,Neuroradiologi,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Faculty of Medicine,Neuroradiology,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Skåne University Hospital(Swepub:lu)med-psu (author)
Siesjö, PeterLund University,Lunds universitet,Glioma immunterapigrupp,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Glioma immunotherapy group,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Skåne University Hospital(Swepub:lu)nkir-psi (author)
Elfving, MariaLund University,Lunds universitet,Pediatrik, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Childhood Cancer Research Unit,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Paediatrics (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Skåne University Hospital(Swepub:lu)pedi-mel (author)
Nilsson, MargaretaLund University,Skåne University Hospital (author)
Pediatrik, LundSektion V (creator_code:org_t)

Related titles

In:Endocrine: Springer Science and Business Media LLC79, s. 152-1601355-008X1559-0100

Internet link

Find in a library

Endocrine (Search for host publication in LIBRIS)

To the university's database

Find more in SwePub

By the author/editor: Borghammar, Cami ...; Tamaddon, Ashkan; Erfurth, Eva-Mar ...; Sundgren, Pia C; Siesjö, Peter; Elfving, Maria; show more...; Nilsson, Margare ...; show less...

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Radiology Nuclea ...

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Pediatrics

Articles in the publication: Endocrine

By the university: Lund University

Search outside SwePub

Extend your search to:: Google; Google Book Search; Google Scholar

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

LIBRIS.kb.se