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Consumption of ultr...
Consumption of ultraprocessed food and development of chronic kidney disease : the Tianjin Chronic Low-Grade Systemic Inflammation and Health and UK Biobank Cohort Studies
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- Gu, Yeqing (author)
- Peking Union Medical College
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- Li, Huiping (author)
- Tianjin Medical University
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- Ma, Hao (author)
- Tulane University
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- Zhang, Shunming (author)
- Tianjin Medical University
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- Meng, Ge (author)
- Tianjin Medical University
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- Zhang, Qing (author)
- Tianjin Medical University General Hospital
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- Liu, Li (author)
- Tianjin Medical University General Hospital
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- Wu, Hongmei (author)
- Tianjin Medical University
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- Zhang, Tingjing (author)
- Tianjin Medical University
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- Wang, Xuena (author)
- Tianjin Medical University
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- Zhang, Juanjuan (author)
- Tianjin Medical University
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- Sun, Shaomei (author)
- Tianjin Medical University General Hospital
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- Wang, Xing (author)
- Tianjin Medical University General Hospital
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- Zhou, Ming (author)
- Tianjin Medical University General Hospital
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Jia, Qiyu (author)
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Song, Kun (author)
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Liu, Qiang (author)
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Huang, Tao (author)
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- Borné, Yan (author)
- Lund University,Lunds universitet,Nutritionsepidemiologi,Forskargrupper vid Lunds universitet,Nutrition Epidemiology,Lund University Research Groups
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Wang, Yaogang (author)
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Qi, Lu (author)
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Niu, Kaijun (author)
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(creator_code:org_t)
- Elsevier BV, 2023
- 2023
- English.
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In: The American journal of clinical nutrition. - : Elsevier BV. - 1938-3207 .- 0002-9165. ; 117:2, s. 373-382
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http://dx.doi.org/10...
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https://lup.lub.lu.s...
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Abstract
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- BackgroundMany ultraprocessed food (UPF)-derived by-products may play a role in the development of chronic kidney disease (CKD). Although several studies have assessed the association of UPFs with kidney function decline or CKD in various countries, no evidence has been shown in China and the United Kingdom.ObjectivesThis study aims to evaluate the association between UPF consumption and risk of CKD in 2 large cohort studies from China and the United Kingdom.MethodsIn total, 23,775 and 102,332 participants without baseline CKD were enrolled in the Tianjin Chronic Low-Grade Systemic Inflammation and Health (TCLSIH) and UK Biobank cohort studies, respectively. Information on UPF consumption was obtained from a validated food frequency questionnaire in the TCLSIH and 24-h dietary recalls in the UK Biobank cohort. CKD was defined as an estimated glomerular filtration rate of ResultsAfter a median follow-up of 4.0 and 10.1 y, the incidence rates of CKD were around 1.1% and 1.7% in the TCLSIH and UK Biobank cohorts, respectively. The multivariable hazard ratio [95% confidence interval] of CKD across increasing quartiles (quartiles 1–4) of UPF consumption were 1 (reference), 1.24 (0.89, 1.72), 1.30 (0.91, 1.87), and 1.58 (1.07, 2.34) (P for trend = 0.02) in the TCLSIH cohort and 1 (reference), 1.14 (1.00, 1.31), 1.16 (1.01, 1.33), and 1.25 (1.09, 1.43) (P for trend < 0.01) in the UK Biobank cohort, respectively.ConclusionsOur finding indicated that higher UPF consumption is associated with a higher risk of CKD. Moreover, restricting UPF consumption may potentially benefit the prevention of CKD. Further clinical trials are required to clarify the causality.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Näringslära (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Nutrition and Dietetics (hsv//eng)
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- art (subject category)
- ref (subject category)
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- By the author/editor
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Gu, Yeqing
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Li, Huiping
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Ma, Hao
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Zhang, Shunming
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Meng, Ge
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Zhang, Qing
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show more...
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Liu, Li
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Wu, Hongmei
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Zhang, Tingjing
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Wang, Xuena
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Zhang, Juanjuan
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Sun, Shaomei
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Wang, Xing
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Zhou, Ming
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Jia, Qiyu
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Song, Kun
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Liu, Qiang
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Huang, Tao
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Borné, Yan
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Wang, Yaogang
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Qi, Lu
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Niu, Kaijun
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Health Sciences
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and Nutrition and Di ...
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The American jou ...
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Lund University