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Chemoprophylaxis, d...
Chemoprophylaxis, diagnosis, treatments, and discharge management of COVID-19 : An evidence-based clinical practice guideline (updated version)
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- Jin, Ying-Hui (författare)
- Wuhan University
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- Zhan, Qing-Yuan (författare)
- Beijing Friendship Hospital
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- Peng, Zhi-Yong (författare)
- Wuhan University
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- Ren, Xue-Qun (författare)
- Henan University
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Yin, Xun-Tao (författare)
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- Cai, Lin (författare)
- Wuhan University
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- Yuan, Yu-Feng (författare)
- Wuhan University
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- Yue, Ji-Rong (författare)
- Sichuan University
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- Zhang, Xiao-Chun (författare)
- Zhongnan Hospital of Wuhan University
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- Yang, Qi-Wen (författare)
- Chinese Academy of Sciences
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- Ji, Jianguang (författare)
- Lund University,Lunds universitet,Allmänmedicin och klinisk epidemiologi,Forskargrupper vid Lunds universitet,Family Medicine and Clinical Epidemiology,Lund University Research Groups,Region Skåne
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- Xia, Jian (författare)
- Wuhan University
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- Li, Yi-Rong (författare)
- Wuhan University
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- Zhou, Fu-Xiang (författare)
- Wuhan University
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- Gao, Ya-Dong (författare)
- Wuhan University
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- Yu, Zhui (författare)
- Wuhan University
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- Xu, Feng (författare)
- Shandong University
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- Tu, Ming-Li (författare)
- Shandong University
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Tan, Li-Ming (författare)
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- Yang, Min (författare)
- Anhui Polytechnic University
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- Chen, Fang (författare)
- Zhengzhou University
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- Zhang, Xiao-Ju (författare)
- Henan University
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- Zeng, Mei (författare)
- Fudan University
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- Zhu, Yu (författare)
- Sichuan University
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- Liu, Xin-Can (författare)
- Henan University
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Yang, Jian (författare)
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- Zhao, Dong-Chi (författare)
- Wuhan University
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- Ding, Yu-Feng (författare)
- Huazhong University of Science and Technology
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- Hou, Ning (författare)
- Shandong First Medical University
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- Wang, Fu-Bing (författare)
- Wuhan University
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- Chen, Hao (författare)
- Nanjing University
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- Zhang, Yong-Gang (författare)
- Sichuan University
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- Li, Wei (författare)
- Qingdao University
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- Chen, Wen (författare)
- Hubei University
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- Shi, Yue-Xian (författare)
- Peking University
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- Yang, Xiu-Zhi (författare)
- Kaifeng Central Hospital
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- Wang, Xue-Jun (författare)
- Beijing Electric Power Hospital
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- Zhong, Yan-Jun (författare)
- Central South University, China
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- Zhao, Ming-Juan (författare)
- Wuhan University
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- Li, Bing-Hui (författare)
- Wuhan University
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- Ma, Lin-Lu (författare)
- Wuhan University
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- Zi, Hao (författare)
- Henan University
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- Wang, Na (författare)
- Henan University
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- Wang, Yun-Yun (författare)
- Wuhan University
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- Yu, Shao-Fu (författare)
- Second People's Hospital of Huaihua City
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- Li, Lu-Yao (författare)
- Henan University
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- Huang, Qiao (författare)
- Wuhan University
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- Weng, Hong (författare)
- Wuhan University
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- Ren, Xiang-Ying (författare)
- Wuhan University
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- Yu, Lin-Xin (författare)
- Wuhan University
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- 2020-09-04
- 2020
- Engelska.
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Ingår i: Military Medical Research. - : Springer Science and Business Media LLC. - 2054-9369. ; 7:1
- Relaterad länk:
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http://dx.doi.org/10... (free)
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https://mmrjournal.b...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of a rapidly spreading illness, coronavirus disease 2019 (COVID-19), affecting more than seventeen million people around the world. Diagnosis and treatment guidelines for clinicians caring for patients are needed. In the early stage, we have issued "A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus (2019-nCoV) infected pneumonia (standard version)"; now there are many direct evidences emerged and may change some of previous recommendations and it is ripe for develop an evidence-based guideline. We formed a working group of clinical experts and methodologists. The steering group members proposed 29 questions that are relevant to the management of COVID-19 covering the following areas: chemoprophylaxis, diagnosis, treatments, and discharge management. We searched the literature for direct evidence on the management of COVID-19, and assessed its certainty generated recommendations using the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach. Recommendations were either strong or weak, or in the form of ungraded consensus-based statement. Finally, we issued 34 statements. Among them, 6 were strong recommendations for, 14 were weak recommendations for, 3 were weak recommendations against and 11 were ungraded consensus-based statement. They covered topics of chemoprophylaxis (including agents and Traditional Chinese Medicine (TCM) agents), diagnosis (including clinical manifestations, reverse transcription-polymerase chain reaction (RT-PCR), respiratory tract specimens, IgM and IgG antibody tests, chest computed tomography, chest x-ray, and CT features of asymptomatic infections), treatments (including lopinavir-ritonavir, umifenovir, favipiravir, interferon, remdesivir, combination of antiviral drugs, hydroxychloroquine/chloroquine, interleukin-6 inhibitors, interleukin-1 inhibitors, glucocorticoid, qingfei paidu decoction, lianhua qingwen granules/capsules, convalescent plasma, lung transplantation, invasive or noninvasive ventilation, and extracorporeal membrane oxygenation (ECMO)), and discharge management (including discharge criteria and management plan in patients whose RT-PCR retesting shows SARS-CoV-2 positive after discharge). We also created two figures of these recommendations for the implementation purpose. We hope these recommendations can help support healthcare workers caring for COVID-19 patients.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Infektionsmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Infectious Medicine (hsv//eng)
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Jin, Ying-Hui
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Zhan, Qing-Yuan
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Peng, Zhi-Yong
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Ren, Xue-Qun
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Yin, Xun-Tao
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Cai, Lin
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visa fler...
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Yuan, Yu-Feng
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Yue, Ji-Rong
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Zhang, Xiao-Chun
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Yang, Qi-Wen
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Ji, Jianguang
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Xia, Jian
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Li, Yi-Rong
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Zhou, Fu-Xiang
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Gao, Ya-Dong
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Yu, Zhui
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Xu, Feng
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Tu, Ming-Li
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Tan, Li-Ming
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Yang, Min
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Chen, Fang
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Zhang, Xiao-Ju
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Zeng, Mei
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Zhu, Yu
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Liu, Xin-Can
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Yang, Jian
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Zhao, Dong-Chi
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Ding, Yu-Feng
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Hou, Ning
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Wang, Fu-Bing
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Chen, Hao
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Zhang, Yong-Gang
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Li, Wei
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Chen, Wen
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Shi, Yue-Xian
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Yang, Xiu-Zhi
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Wang, Xue-Jun
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Zhong, Yan-Jun
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Zhao, Ming-Juan
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Li, Bing-Hui
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Ma, Lin-Lu
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Zi, Hao
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Wang, Na
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Wang, Yun-Yun
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Yu, Shao-Fu
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Li, Lu-Yao
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Huang, Qiao
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Weng, Hong
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Ren, Xiang-Ying
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Yu, Lin-Xin
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