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Chemoprophylaxis, d...
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Jin, Ying-HuiWuhan University
(author)
Chemoprophylaxis, diagnosis, treatments, and discharge management of COVID-19 : An evidence-based clinical practice guideline (updated version)
- Article/chapterEnglish2020
Publisher, publication year, extent ...
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2020-09-04
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Springer Science and Business Media LLC,2020
Numbers
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LIBRIS-ID:oai:lup.lub.lu.se:8390698c-5063-4b1c-8a23-6188294b4123
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https://lup.lub.lu.se/record/8390698c-5063-4b1c-8a23-6188294b4123URI
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https://doi.org/10.1186/s40779-020-00270-8DOI
Supplementary language notes
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Language:English
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Summary in:English
Part of subdatabase
Classification
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Subject category:art swepub-publicationtype
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Subject category:ref swepub-contenttype
Notes
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The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of a rapidly spreading illness, coronavirus disease 2019 (COVID-19), affecting more than seventeen million people around the world. Diagnosis and treatment guidelines for clinicians caring for patients are needed. In the early stage, we have issued "A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus (2019-nCoV) infected pneumonia (standard version)"; now there are many direct evidences emerged and may change some of previous recommendations and it is ripe for develop an evidence-based guideline. We formed a working group of clinical experts and methodologists. The steering group members proposed 29 questions that are relevant to the management of COVID-19 covering the following areas: chemoprophylaxis, diagnosis, treatments, and discharge management. We searched the literature for direct evidence on the management of COVID-19, and assessed its certainty generated recommendations using the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach. Recommendations were either strong or weak, or in the form of ungraded consensus-based statement. Finally, we issued 34 statements. Among them, 6 were strong recommendations for, 14 were weak recommendations for, 3 were weak recommendations against and 11 were ungraded consensus-based statement. They covered topics of chemoprophylaxis (including agents and Traditional Chinese Medicine (TCM) agents), diagnosis (including clinical manifestations, reverse transcription-polymerase chain reaction (RT-PCR), respiratory tract specimens, IgM and IgG antibody tests, chest computed tomography, chest x-ray, and CT features of asymptomatic infections), treatments (including lopinavir-ritonavir, umifenovir, favipiravir, interferon, remdesivir, combination of antiviral drugs, hydroxychloroquine/chloroquine, interleukin-6 inhibitors, interleukin-1 inhibitors, glucocorticoid, qingfei paidu decoction, lianhua qingwen granules/capsules, convalescent plasma, lung transplantation, invasive or noninvasive ventilation, and extracorporeal membrane oxygenation (ECMO)), and discharge management (including discharge criteria and management plan in patients whose RT-PCR retesting shows SARS-CoV-2 positive after discharge). We also created two figures of these recommendations for the implementation purpose. We hope these recommendations can help support healthcare workers caring for COVID-19 patients.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
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Zhan, Qing-YuanBeijing Friendship Hospital
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Peng, Zhi-YongWuhan University
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Ren, Xue-QunHenan University
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Yin, Xun-Tao
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Cai, LinWuhan University
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Yuan, Yu-FengWuhan University
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Yue, Ji-RongSichuan University
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Zhang, Xiao-ChunZhongnan Hospital of Wuhan University
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Yang, Qi-WenChinese Academy of Sciences
(author)
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Ji, JianguangLund University,Lunds universitet,Allmänmedicin och klinisk epidemiologi,Forskargrupper vid Lunds universitet,Family Medicine and Clinical Epidemiology,Lund University Research Groups,Region Skåne(Swepub:lu)med-jji
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Xia, JianWuhan University
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Li, Yi-RongWuhan University
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Zhou, Fu-XiangWuhan University
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Gao, Ya-DongWuhan University
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Yu, ZhuiWuhan University
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Xu, FengShandong University
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Tu, Ming-LiShandong University
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Tan, Li-Ming
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Yang, MinAnhui Polytechnic University(Swepub:lu)med-myn
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Chen, FangZhengzhou University
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Zhang, Xiao-JuHenan University
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Zeng, MeiFudan University
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Zhu, YuSichuan University
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Liu, Xin-CanHenan University
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Yang, Jian
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Zhao, Dong-ChiWuhan University
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Ding, Yu-FengHuazhong University of Science and Technology
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Hou, NingShandong First Medical University
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Wang, Fu-BingWuhan University
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Chen, HaoNanjing University
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Zhang, Yong-GangSichuan University
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Li, WeiQingdao University
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Chen, WenHubei University
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Shi, Yue-XianPeking University
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Yang, Xiu-ZhiKaifeng Central Hospital
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Wang, Xue-JunBeijing Electric Power Hospital
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Zhong, Yan-JunCentral South University, China
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Zhao, Ming-JuanWuhan University
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Li, Bing-HuiWuhan University
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Ma, Lin-LuWuhan University
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Zi, HaoHenan University
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Wang, NaHenan University
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Wang, Yun-YunWuhan University
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Yu, Shao-FuSecond People's Hospital of Huaihua City
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Li, Lu-YaoHenan University
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Huang, QiaoWuhan University
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Weng, HongWuhan University
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Ren, Xiang-YingWuhan University
(author)
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Yu, Lin-XinWuhan University
(author)
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Wuhan UniversityBeijing Friendship Hospital
(creator_code:org_t)
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Evidence-Based Medicine Chapter of China International Exchange and Promotive Association for Medical and Health Care (CPAM)
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Chinese Research Hospital Association (CRHA
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Infectious Medic ...
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Military Medical ...
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Lund University