Online monitoring of urea concentration in dialysate with dual-beam Fourier-transform near-infrared spectroscopy

The robustness of a dual-beam, optical null, Fourier-transform near-infrared (FTNIR) spectrometer was investigated by means of online, near-infrared measurements and predictions of urea concentrations in spent dialysate during hemodialysis treatment. Simple multivariate calibration using a few factors based on a small number of prepared samples provided stable and accurate predictions over a period of 1 month. The calibration was robust when faced with adjustment of reference cell intensity and did not require a daily measured reference spectrum. The root-mean-square error of prediction of urea was 0.4 mM based on a two-factor partial least-squares regression model. (C) 2004 Society of Photo-Optical Instrumentation Engineers.

Bak, J (författare)
Ladefoged, S (författare)
Andersson-Engels, StefanLund University,Lunds universitet,Atomfysik,Fysiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Atomic Physics,Department of Physics,Departments at LTH,Faculty of Engineering, LTH(Swepub:lu)fysi-san (författare)
Friis-Hansen, L (författare)
AtomfysikFysiska institutionen (creator_code:org_t)

Ingår i:Journal of Biomedical Optics: SPIE-Intl Soc Optical Eng9:3, s. 553-5571083-3668

Av författaren/redakt...: Jensen, PS; Bak, J; Ladefoged, S; Andersson-Engels ...; Friis-Hansen, L

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