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  • Akil, ShahnazLund University,Lunds universitet,Hjärt-MR-gruppen i Lund,Forskargrupper vid Lunds universitet,Lund Cardiac MR Group,Lund University Research Groups,Princess Nourah bint Abdulrahman University,Skåne University Hospital (author)

Appropriate coronary revascularization can be accomplished if myocardial perfusion is quantified by positron emission tomography prior to treatment decision

  • Article/chapterEnglish2021

Publisher, publication year, extent ...

  • 2019-11-08
  • Springer Science and Business Media LLC,2021
  • 9 s.

Numbers

  • LIBRIS-ID:oai:lup.lub.lu.se:85f64307-a207-45e9-9481-03980e7cd4ea
  • https://lup.lub.lu.se/record/85f64307-a207-45e9-9481-03980e7cd4eaURI
  • https://doi.org/10.1007/s12350-019-01938-yDOI

Supplementary language notes

  • Language:English
  • Summary in:English

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  • Subject category:art swepub-publicationtype
  • Subject category:ref swepub-contenttype

Notes

  • Background: Many patients undergo percutaneous coronary intervention (PCI) without the use of non-invasive stress testing prior to treatment. The aim of this study was to determine the potential added value of guiding revascularization by quantitative assessment of myocardial perfusion prior to intervention. Methods and Results: Thirty-three patients (10 females) with suspected or established CAD who had been referred for a clinical coronary angiography (CA) with possibility for PCI were included. Adenosine stress and rest 13N-NH3 PET, cardiac magnetic resonance (CMR), and cardiopulmonary exercise test were performed 4 ± 3 weeks before and 5 ± 1 months after CA. The angiographer was blinded to the PET and CMR results. Myocardial flow reserve (MFR) < 2.0 by PET was considered abnormal. A PCI was performed in 19/33 patients. In 41% (11/27) of the revascularized vessel territories, a normal regional MFR was found prior to the PCI and no improvement in MFR was found at follow-up (P = 0.9). However, vessel territories with regional MFR < 2.0 at baseline improved significantly after PCI (P = 0.003). Of the 14 patients not undergoing PCI, four had MFR < 2.0 in one or more coronary territories. Conclusion: Assessment of quantitative myocardial perfusion prior to revascularization could lead to more appropriate use of CA when managing patients with stable CAD.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Hedeer, FredrikLund University,Lunds universitet,Hjärt-MR-gruppen i Lund,Forskargrupper vid Lunds universitet,Lund Cardiac MR Group,Lund University Research Groups,Skåne University Hospital(Swepub:lu)med-fkh (author)
  • Oddstig, JennySkåne University Hospital(Swepub:lu)med-jot (author)
  • Olsson, ThomasSkåne University Hospital (author)
  • Jögi, JonasLund University,Lunds universitet,Hjärt-MR-gruppen i Lund,Forskargrupper vid Lunds universitet,Lund Cardiac MR Group,Lund University Research Groups,Skåne University Hospital(Swepub:lu)klin-jjo (author)
  • Erlinge, DavidLund University,Lunds universitet,Molekylär kardiologi,Forskargrupper vid Lunds universitet,Molecular Cardiology,Lund University Research Groups,Skåne University Hospital(Swepub:lu)kard-der (author)
  • Carlsson, MarcusLund University,Lunds universitet,Hjärt-MR-gruppen i Lund,Forskargrupper vid Lunds universitet,Lund Cardiac MR Group,Lund University Research Groups,Skåne University Hospital(Swepub:lu)klin-mca (author)
  • Arheden, HåkanLund University,Lunds universitet,Hjärt-MR-gruppen i Lund,Forskargrupper vid Lunds universitet,Lund Cardiac MR Group,Lund University Research Groups,Skåne University Hospital(Swepub:lu)klfy-har (author)
  • Hindorf, CeciliaSkåne University Hospital(Swepub:lu)rafy-chi (author)
  • Engblom, HenrikLund University,Lunds universitet,Hjärt-MR-gruppen i Lund,Forskargrupper vid Lunds universitet,Lund Cardiac MR Group,Lund University Research Groups,Skåne University Hospital(Swepub:lu)klin-hen (author)
  • Hjärt-MR-gruppen i LundForskargrupper vid Lunds universitet (creator_code:org_t)

Related titles

  • In:Journal of Nuclear Cardiology: Springer Science and Business Media LLC28:4, s. 1664-16721071-35811532-6551

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