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  • Ripsweden, JonazKarolinska Institutet (author)

Impact on image quality and radiation exposure in coronary CT angiography: 100 kVp versus 120 kVp

  • Article/chapterEnglish2010

Publisher, publication year, extent ...

  • 2010-10-01
  • SAGE Publications,2010

Numbers

  • LIBRIS-ID:oai:lup.lub.lu.se:873ffc1e-c6d6-48b9-8234-0b3c2f4f72f6
  • https://lup.lub.lu.se/record/1728191URI
  • https://doi.org/10.3109/02841851.2010.504740DOI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:121362507URI

Supplementary language notes

  • Language:English
  • Summary in:English

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  • Subject category:art swepub-publicationtype
  • Subject category:ref swepub-contenttype

Notes

  • Background: The risk of radiation-induced cancer has become a major concern with the increasing use of computed tomography (CT). Purpose: To compare image quality and radiation doses when decreasing X-ray tube peak kilovoltage (kVp) from 120 to 100 kVp in patients undergoing coronary CT angiography (CCTA). Material and Methods: Patients referred for evaluation of suspected coronary artery disease (CAD) underwent 64-channel detector CCTA using a tube voltage of either 120 kVp (n = 46) or 100 kVp (n = 82). The individual volume CT dose index (CTDIvol) and dose length product (DLP) were recorded and effective radiation dose was estimated on the basis of DLP. Subjective image quality was assessed by two radiologists on per-patient based consensus. Vascular density and image noise were quantified in the left main coronary artery (LMCA) and proximal ascending aorta (AA). Mean density in the adjacent perivascular tissue was also quantified. Contrast-to-noise ratio (CNR) was calculated. Corresponding invasive coronary angiography (ICA) was performed, which constituted the gold standard. Results: Mean values in the 100120 kVp cohorts regarding CNR in the LMCA were 12.716.0 (P < 0.0001)) and in the AA 13.217.2 (P < 0.0001), CTDIvol 34.457.4 mGy (a 40% reduction, P < 0.0001), DLP 5781125 mGy X cm (P < 0.0001), and estimated effective dose 9.620.2 mSv (P < 0.0001). There was no statistically significant difference in subjective image quality between the two cohorts. The sensitivity to detect significant coronary stenoses was 88% (120 kVp) and 84% (100 kVp) and the specificity was 71% (120 kVp) and 74% (100 kVp), respectively. Conclusion: By reduction of tube voltage from 120 to 100 kVp at CCTA, while keeping all other scanning parameters unchanged, the radiation dose to the patient can be almost halved while keeping the diagnostic image quality at a clinically acceptable level.

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  • Brismar, Torkel B.Karolinska Institutet (author)
  • Holm, Jon (author)
  • Melinder, Annika (author)
  • Mir-Akbari, HabibKarolinska Institutet (author)
  • Nilsson, Tage (author)
  • Nyman, UlfLund University,Lunds universitet,Diagnostisk radiologi, Malmö,Forskargrupper vid Lunds universitet,Radiology Diagnostics, Malmö,Lund University Research Groups(Swepub:lu)ront-uny (author)
  • Rasmussen, Elsbeth (author)
  • Ruck, AndreasKarolinska Institutet (author)
  • Cederlund, KerstinKarolinska Institutet (author)
  • Karolinska InstitutetDiagnostisk radiologi, Malmö (creator_code:org_t)

Related titles

  • In:Acta Radiologica: SAGE Publications51:8, s. 903-9091600-04550284-1851

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