Sökning: WFRF:(Sabbah Muhammad) >
Long-term prognosti...
Long-term prognostic outcomes and implication of oral anticoagulants in patients with new-onset atrial fibrillation following st-segment elevation myocardial infarction
-
- Madsen, Jasmine Melissa (författare)
- Copenhagen University Hospital
-
- Jacobsen, Mia Ravn (författare)
- Copenhagen University Hospital
-
- Sabbah, Muhammad (författare)
- Copenhagen University Hospital
-
visa fler...
-
- Topal, Divan Gabriel (författare)
- Copenhagen University Hospital
-
- Jabbari, Reza (författare)
- Copenhagen University Hospital
-
- Glinge, Charlotte (författare)
- Copenhagen University Hospital
-
- Køber, Lars (författare)
- Copenhagen University Hospital
-
- Torp-Pedersen, Christian (författare)
- Hillerod Hospital,Aalborg University Hospital
-
- Pedersen, Frants (författare)
- Copenhagen University Hospital
-
- Sørensen, Rikke (författare)
- Copenhagen University Hospital
-
- Holmvang, Lene (författare)
- Copenhagen University Hospital
-
- Engstrøm, Thomas (författare)
- Lund University,Lunds universitet,Kardiologi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Cardiology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Copenhagen University Hospital
-
- Lønborg, Jacob Thomsen (författare)
- Copenhagen University Hospital
-
visa färre...
-
(creator_code:org_t)
- Elsevier BV, 2021
- 2021
- Engelska 11 s.
-
Ingår i: American Heart Journal. - : Elsevier BV. - 0002-8703. ; 238, s. 89-99
- Relaterad länk:
-
http://dx.doi.org/10... (free)
-
visa fler...
-
https://doi.org/10.1...
-
https://lup.lub.lu.s...
-
https://doi.org/10.1...
-
visa färre...
Abstract
Ämnesord
Stäng
- Background: New-onset atrial fibrillation (NEW-AF) following ST-segment elevation myocardial infarction (STEMI) is a common complication, but the true prognostic impact of NEW-AF is unknown. Additionally, the optimal treatment of NEW-AF among patients with STEMI is warranted. Methods: A large cohort of consecutive patients with STEMI treated with percutaneous coronary intervention were identified using the Eastern Danish Heart Registry from 1999-2016. Medication and end points were retrieved from Danish nationwide registries. NEW-AF was defined as a diagnosis of AF within 30 days following STEMI. Patients without a history of AF and alive after 30 days after discharge were included. Incidence rates were calculated and multivariate analyses performed to determine the association between NEW-AF and long-term mortality, incidence of ischemic stroke, re-MI, and bleeding leading to hospitalization, and the comparative effectiveness of OAC therapy on these outcomes. Results: Of 7944 patients with STEMI, 296 (3.7%) developed NEW-AF. NEW-AF was associated with increased long-term mortality (adjusted HR 1.48, 95% CI 1.20-1.82, P<.001) and risk of bleeding leading to hospitalization (adjusted HR 1.36, 95% CI 1.00-1.85, P=.050), and non-significant increased risk of ischemic stroke (adjusted HR 1.45, 95% CI 0.96-2.19, P=.08) and re-MI (adjusted HR 1.14, 95% CI 0.86-1.52, P=.35) with a median follow-up of 5.8 years. In NEW-AF patients, 38% received OAC therapy, which was associated with reduced long-term mortality (adjusted HR 0.69, 95% CI 0.47-1.00, P=.049). Conclusions: NEW-AF following STEMI is associated with increased long-term mortality. Treatment with OAC therapy in NEW-AF patients is associated with reduced long-term mortality.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Nyckelord
- None
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
-
Madsen, Jasmine ...
-
Jacobsen, Mia Ra ...
-
Sabbah, Muhammad
-
Topal, Divan Gab ...
-
Jabbari, Reza
-
Glinge, Charlott ...
-
visa fler...
-
Køber, Lars
-
Torp-Pedersen, C ...
-
Pedersen, Frants
-
Sørensen, Rikke
-
Holmvang, Lene
-
Engstrøm, Thomas
-
Lønborg, Jacob T ...
-
visa färre...
- Om ämnet
-
- MEDICIN OCH HÄLSOVETENSKAP
-
MEDICIN OCH HÄLS ...
-
och Klinisk medicin
-
och Kardiologi
- Artiklar i publikationen
-
American Heart J ...
- Av lärosätet
-
Lunds universitet