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Electrocardiographi...
Electrocardiographic scores of severity and acuteness of myocardial ischemia predict myocardial salvage in patients with anterior ST-segment elevation myocardial infarction
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- Fakhri, Yama (författare)
- Copenhagen University Hospital
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- Sejersten, Maria (författare)
- Herlev Hospital
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- Schoos, Mikkel Malby (författare)
- Zealand University Hospital
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- Hansen, Henrik Steen (författare)
- Odense University Hospital
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- Dubois-Rande, Jean Luc (författare)
- Henri Mondor Hospital
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- Hall, Trygve S. (författare)
- Oslo university hospital
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- Larsen, Alf Inge (författare)
- Stavanger University Hospital
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- Jensen, Svend Eggert (författare)
- Aalborg University
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- Engblom, Henrik (författare)
- Lund University,Lunds universitet,Klinisk fysiologi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Hjärt-MR-gruppen i Lund,Forskargrupper vid Lunds universitet,Clinical Physiology (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund Cardiac MR Group,Lund University Research Groups,Skåne University Hospital
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Arheden, Hakon (författare)
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- Kastrup, Jens (författare)
- Copenhagen University Hospital
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- Atar, Dan (författare)
- Oslo university hospital
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Clemmensen, Peter (författare)
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(creator_code:org_t)
- Elsevier BV, 2018
- 2018
- Engelska.
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Ingår i: Journal of Electrocardiology. - : Elsevier BV. - 0022-0736. ; 51:2, s. 195-202
- Relaterad länk:
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http://dx.doi.org/10...
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https://findresearch...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Background: Terminal "QRS distortion" on the electrocardiogram (ECG) (based on Sclarovsky-Birnbaum's Grades of Ischemia Score) is a sign of severe ischemia, associated with adverse cardiovascular outcome in ST-segment elevation myocardial infarction (STEMI). In addition, ECG indices of the acuteness of ischemia (based on Anderson-Wilkins Acuteness Score) indicate myocardial salvage potential. We assessed whether severe ischemia with or without acute ischemia is predictive of infarct size (IS), myocardial salvage index (MSI) and left ventricular ejection fraction (LVEF) in anterior versus inferior infarct locations. Methods: In STEMI patients, the severity and acuteness scores were obtained from the admission ECG. Based on the ECG patients were assigned with severe or non-severe ischemia and acute or non-acute ischemia. Cardiac magnetic resonance (CMR) was performed 2-6. days after primary percutaneous coronary intervention (pPCI). LVEF was measured by echocardiography 30. days after pPCI. Results: ECG analysis of 85 patients with available CMR resulted in 20 (23%) cases with severe and non-acute ischemia, 43 (51%) with non-severe and non-acute ischemia, 17 (20%) with non-severe and acute ischemia, and 5 (6%) patients with severe and acute ischemia. In patients with anterior STEMI (n = 35), ECG measures of severity and acuteness of ischemia identified significant and stepwise differences in myocardial damage and function. Patients with severe and non-acute ischemia had the largest IS, smallest MSI and lowest LVEF. In contrast, no difference was observed in patients with inferior STEMI (n = 50). Conclusions: The applicability of ECG indices of severity and acuteness of myocardial ischemia to estimate myocardial damage and salvage potential in STEMI patients treated with pPCI, is confined to anterior myocardial infarction.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
Nyckelord
- Acuteness of myocardial ischemia
- ECG
- Severity of myocardial ischemia
- STEMI
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
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Fakhri, Yama
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Sejersten, Maria
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Schoos, Mikkel M ...
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Hansen, Henrik S ...
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Dubois-Rande, Je ...
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Hall, Trygve S.
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Larsen, Alf Inge
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Jensen, Svend Eg ...
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Engblom, Henrik
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Arheden, Hakon
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Kastrup, Jens
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Atar, Dan
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Clemmensen, Pete ...
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