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Co-expression of Tr...
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Kokaia, ZaalLund University,Lunds universitet,Neurologi, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Neurology, Lund,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine
(författare)
Co-expression of TrkB and TrkC receptors in CNS neurones suggests regulation by multiple neurotrophins
- Artikel/kapitelEngelska1995
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Ovid Technologies (Wolters Kluwer Health),1995
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LIBRIS-ID:oai:lup.lub.lu.se:8f1c4283-e2a8-4a3d-89cb-28bb41f7233d
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https://lup.lub.lu.se/record/1109370URI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:1931122URI
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https://doi.org/10.1097/00001756-199503270-00016DOI
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Språk:engelska
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Sammanfattning på:engelska
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Using double-label in situ hybridization, we have explored the possibility that individual CNS neurones can co-express mRNAs for the high-affinity receptors of brain-derived neurotrophic factor and neurotrophin-3, TrkB and TrkC, respectively. The vast majority of TrkC mRNA-containing neurones in the hippocampal formation and cerebral cortex were also labelled for TrkB mRNA. Cells expressing only TrkB or TrkC mRNA were very scarce in these regions, representing < 15% of all labelled cells. These findings suggest that the same cortical or hippocampal neurone can be regulated by several members of the neurotrophin family, which may be important both during development and in response to physiological activity and pathological conditions.
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Metsis, Madis
(författare)
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Kokaia, MerabLund University,Lunds universitet,Neurologi, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Neurology, Lund,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)neur-mko
(författare)
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Elmer, EskilLund University,Lunds universitet,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)expb-eel
(författare)
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Lindvall, OlleLund University,Lunds universitet,Neurologi, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Neurology, Lund,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)neur-oli
(författare)
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Neurologi, LundSektion IV
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:NeuroReport: Ovid Technologies (Wolters Kluwer Health)6:5, s. 769-7721473-558X0959-4965
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