id:"swepub:oai:lup.lub.lu.se:9308b5ff-7dc4-49ac-bec5-02bc69e17204"
Search: id:"swepub:oai:lup.lub.lu.se:9308b5ff-7dc4-49ac-bec5-02bc69e17204" > Short- and long-ter...
- 1 of 1
- Previous record
- Next record
- To hitlist
- Tobler, MichaelLund University,Lunds universitet,MEMEG,Biologiska institutionen,Naturvetenskapliga fakulteten,Department of Biology,Faculty of Science (author)
Short- and long-term consequences of prenatal testosterone for immune function: an experimental study in the zebra finch
- Article/chapterEnglish2010
Publisher, publication year, extent ...
- 2009-12-15
- Springer Science and Business Media LLC,2010
Numbers
- LIBRIS-ID:oai:lup.lub.lu.se:9308b5ff-7dc4-49ac-bec5-02bc69e17204
- https://lup.lub.lu.se/record/1588130URI
- https://doi.org/10.1007/s00265-009-0889-0DOI
Supplementary language notes
- Language:English
- Summary in:English
Part of subdatabase
- SwePubSwePub
Classification
Notes
- Hormone-mediated maternal effects play an important role in the formation of a differentiated phenotype. They have been shown to influence a wide array of offspring traits, both early in life and in adulthood. One important offspring trait that is under the influence of maternal androgens is the immune system. In birds, a growing number of studies show that yolk androgens modulate immune function during the chick stage. However, there is a lack of knowledge regarding long-term effects of prenatal androgens on offspring immunity. In this study, we therefore investigated the influence of prenatal testosterone (T) on several measures of immunity in fledgling and adult zebra finches (Taeniopygia guttata). Cell-mediated immune response (towards phytohaemagglutinin, PHA) of fledglings hatching from control eggs was negatively related to brood size, whereas there was no such association for fledglings hatching from eggs with experimentally elevated T levels (T fledglings). Male control fledglings showed reduced mass gain compared to female control fledglings within 24 h after the PHA injection. This pattern was reversed in T fledglings. Total antibody levels in fledglings were not affected by egg treatment. Neither cell-mediated immunity nor total antibody levels in sexually mature zebra finches were influenced by egg treatment. However, there was an immuno-enhancing effect of elevated egg T on both primary and secondary humoral immune responses toward diphtheria and tetanus antigens in ca 5 and 7 month old zebra finches. In addition, the covariation between different immune components differed between T and control offspring, suggesting that egg treatment may have altered the potential trade-offs between different parts of the immune system. Our results suggest that prenatal androgens could be an important factor contributing to individual variation in immune function even in adulthood.
Subject headings and genre
- NATURVETENSKAP Biologi hsv//swe
- NATURAL SCIENCES Biological Sciences hsv//eng
- NATURVETENSKAP Biologi Ekologi hsv//swe
- NATURAL SCIENCES Biological Sciences Ecology hsv//eng
- Maternal effects
- Life history
- Immune function
- Testosterone
Added entries (persons, corporate bodies, meetings, titles ...)
- Hasselquist, DennisLund University,Lunds universitet,MEMEG,Biologiska institutionen,Naturvetenskapliga fakulteten,Department of Biology,Faculty of Science(Swepub:lu)ekol-dha (author)
- Smith, HenrikLund University,Lunds universitet,Biodiversitet,Biologiska institutionen,Naturvetenskapliga fakulteten,MEMEG,Biodiversity,Department of Biology,Faculty of Science(Swepub:lu)ekol-hsm (author)
- Sandell, MariaLund University,Lunds universitet,MEMEG,Biologiska institutionen,Naturvetenskapliga fakulteten,Department of Biology,Faculty of Science(Swepub:lu)ekol-msa (author)
- MEMEGBiologiska institutionen (creator_code:org_t)
Related titles
- In:Behavioral Ecology and Sociobiology: Springer Science and Business Media LLC64:5, s. 717-7271432-07620340-5443
Internet link
Find in a library
- Behavioral Ecology and Sociobiology (Search for host publication in LIBRIS)
To the university's database
- 1 of 1
- Previous record
- Next record
- To hitlist
Find more in SwePub
- By the author/editor
- Tobler, Michael
- Hasselquist, Den ...
- Smith, Henrik
- Sandell, Maria
- About the subject
-
- NATURAL SCIENCES
- NATURAL SCIENCES
- and Biological Scien ...
-
- NATURAL SCIENCES
- NATURAL SCIENCES
- and Biological Scien ...
- and Ecology
- Articles in the publication
- Behavioral Ecolo ...
- By the university
- Lund University
Search outside SwePub
- Extend your search to:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - National Library Systems
- LIBRIS.kb.se
