WFRF:(Sundkvist David)
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- Sundkvist, GöranLund University,Lunds universitet,Institutionen för translationell medicin,Medicinska fakulteten,Department of Translational Medicine,Faculty of Medicine,Skåne University Hospital (author)
Islet cell antibody reactivity with human fetal pancreatic islets
- Article/chapterEnglish1991
Publisher, publication year, extent ...
- 1991
- 7 s.
Numbers
- LIBRIS-ID:oai:lup.lub.lu.se:934c6871-7708-40a5-93f4-f7435f4026f5
- https://lup.lub.lu.se/record/934c6871-7708-40a5-93f4-f7435f4026f5URI
- https://doi.org/10.1016/0168-8227(91)90046-GDOI
Supplementary language notes
- Language:English
- Summary in:English
Part of subdatabase
- SwePubSwePub
Classification
Notes
- To evaluate the possibility of autoimmune processes against pancreatic islets in fetal life, we tested islet cell antibody (ICA) reactivity with 14 fetal pancreata obtained after abortion at the 15th up to the 19th week of gestation. Pancreatic islets positive for a monoclonal proinsulin antibody but non-reactive with ICA negative control serum were found in 9 14 pancreata and all ( 9 9) of them showed a positive reaction with the ICA standard. It is concluded that ICA reactivity may be detected in fetal human pancreata. Further studies on fetal islet cell antibody reactivity in the development of insulin dependent diabetes mellitus (IDDM) are warranted.
Subject headings and genre
- MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Endokrinologi och diabetes hsv//swe
- MEDICAL AND HEALTH SCIENCES Clinical Medicine Endocrinology and Diabetes hsv//eng
- Autoimmunity
- Fetal islets
- Islet cell antibodies
- Islet cell antigens
Added entries (persons, corporate bodies, meetings, titles ...)
- Bergqvist, AgnetaSkåne University Hospital,Lund University (author)
- Weibull, HenrikSkåne University Hospital,Lund University (author)
- Bergqvist, DavidSkåne University Hospital,Lund University (author)
- Fält, KajSkåne University Hospital,Lund University (author)
- Olsson, Mona LandinLund University,Lunds universitet,Institutionen för translationell medicin,Medicinska fakulteten,Department of Translational Medicine,Faculty of Medicine,Skåne University Hospital(Swepub:lu)med-mla (author)
- Lernmark, ÅkeLund University,Lunds universitet,Institutionen för translationell medicin,Medicinska fakulteten,Department of Translational Medicine,Faculty of Medicine,University of Washington, Seattle,Skåne University Hospital(Swepub:lu)endo-ale (author)
- Institutionen för translationell medicinMedicinska fakulteten (creator_code:org_t)
Related titles
- In:Diabetes Research and Clinical Practice14:1, s. 1-70168-8227
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