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Derivation and vali...
Derivation and validation of the systemic lupus international collaborating clinics classification criteria for systemic lupus erythematosus
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Petri, Michelle (author)
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Orbai, Ana-Maria (author)
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Alarcon, Graciela S. (author)
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show more...
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Gordon, Caroline (author)
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Merrill, Joan T. (author)
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Fortin, Paul R. (author)
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Bruce, Ian N. (author)
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Isenberg, David (author)
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Wallace, Daniel J. (author)
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- Nived, Ola (author)
- Lund University,Lunds universitet,Reumatologi och molekylär skelettbiologi,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Rheumatology,Section III,Department of Clinical Sciences, Lund,Faculty of Medicine
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- Sturfelt, Gunnar (author)
- Lund University,Lunds universitet,Reumatologi och molekylär skelettbiologi,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Rheumatology,Section III,Department of Clinical Sciences, Lund,Faculty of Medicine
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Ramsey-Goldman, Rosalind (author)
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Bae, Sang-Cheol (author)
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Hanly, John G. (author)
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Sanchez-Guerrero, Jorge (author)
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Clarke, Ann (author)
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Aranow, Cynthia (author)
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Manzi, Susan (author)
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Urowitz, Murray (author)
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Gladman, Dafna (author)
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Kalunian, Kenneth (author)
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Costner, Melissa (author)
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Werth, Victoria P. (author)
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Zoma, Asad (author)
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Bernatsky, Sasha (author)
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Ruiz-Irastorza, Guillermo (author)
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Khamashta, Munther A. (author)
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Jacobsen, Soren (author)
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Buyon, Jill P. (author)
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Maddison, Peter (author)
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Dooley, Mary Anne (author)
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- van vollenhoven, Ronald F. (author)
- Karolinska Institutet
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Ginzler, Ellen (author)
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Stoll, Thomas (author)
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Peschken, Christine (author)
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Jorizzo, Joseph L. (author)
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Callen, Jeffrey P. (author)
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Lim, S. Sam (author)
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Fessler, Barri J. (author)
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Inanc, Murat (author)
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Kamen, Diane L. (author)
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Rahman, Anisur (author)
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Steinsson, Kristjan (author)
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Franks, Andrew G. (author)
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Sigler, Lisa (author)
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Hameed, Suhail (author)
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Fang, Hong (author)
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Pham, Ngoc (author)
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Brey, Robin (author)
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Weisman, Michael H. (author)
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McGwin, Gerald (author)
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Magder, Laurence S. (author)
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(creator_code:org_t)
- 2012-07-27
- 2012
- English.
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In: Arthritis and Rheumatism. - : Wiley. - 1529-0131 .- 0004-3591. ; 64:8, s. 2677-2686
- Related links:
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http://dx.doi.org/10...
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https://onlinelibrar...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
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- Objective The Systemic Lupus International Collaborating Clinics (SLICC) group revised and validated the American College of Rheumatology (ACR) systemic lupus erythematosus (SLE) classification criteria in order to improve clinical relevance, meet stringent methodology requirements, and incorporate new knowledge regarding the immunology of SLE. Methods The classification criteria were derived from a set of 702 expert-rated patient scenarios. Recursive partitioning was used to derive an initial rule that was simplified and refined based on SLICC physician consensus. The SLICC group validated the classification criteria in a new validation sample of 690 new expert-rated patient scenarios. Results Seventeen criteria were identified. In the derivation set, the SLICC classification criteria resulted in fewer misclassifications compared with the current ACR classification criteria (49 versus 70; P = 0.0082) and had greater sensitivity (94% versus 86%; P < 0.0001) and equal specificity (92% versus 93%; P = 0.39). In the validation set, the SLICC classification criteria resulted in fewer misclassifications compared with the current ACR classification criteria (62 versus 74; P = 0.24) and had greater sensitivity (97% versus 83%; P < 0.0001) but lower specificity (84% versus 96%; P < 0.0001). Conclusion The new SLICC classification criteria performed well in a large set of patient scenarios rated by experts. According to the SLICC rule for the classification of SLE, the patient must satisfy at least 4 criteria, including at least one clinical criterion and one immunologic criterion OR the patient must have biopsy-proven lupus nephritis in the presence of antinuclear antibodies or antidouble-stranded DNA antibodies.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Reumatologi och inflammation (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Rheumatology and Autoimmunity (hsv//eng)
Publication and Content Type
- art (subject category)
- ref (subject category)
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- By the author/editor
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Petri, Michelle
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Orbai, Ana-Maria
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Alarcon, Graciel ...
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Gordon, Caroline
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Merrill, Joan T.
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Fortin, Paul R.
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show more...
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Bruce, Ian N.
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Isenberg, David
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Wallace, Daniel ...
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Nived, Ola
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Sturfelt, Gunnar
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Ramsey-Goldman, ...
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Bae, Sang-Cheol
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Hanly, John G.
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Sanchez-Guerrero ...
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Clarke, Ann
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Aranow, Cynthia
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Manzi, Susan
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Urowitz, Murray
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Gladman, Dafna
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Kalunian, Kennet ...
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Costner, Melissa
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Werth, Victoria ...
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Zoma, Asad
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Bernatsky, Sasha
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Ruiz-Irastorza, ...
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Khamashta, Munth ...
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Jacobsen, Soren
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Buyon, Jill P.
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Maddison, Peter
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Dooley, Mary Ann ...
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van vollenhoven, ...
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Ginzler, Ellen
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Stoll, Thomas
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Peschken, Christ ...
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Jorizzo, Joseph ...
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Callen, Jeffrey ...
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Lim, S. Sam
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Fessler, Barri J ...
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Inanc, Murat
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Kamen, Diane L.
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Rahman, Anisur
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Steinsson, Krist ...
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Franks, Andrew G ...
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Sigler, Lisa
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Hameed, Suhail
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Fang, Hong
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Pham, Ngoc
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Brey, Robin
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Weisman, Michael ...
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McGwin, Gerald
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Magder, Laurence ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Rheumatology and ...
- Articles in the publication
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Arthritis and Rh ...
- By the university
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Lund University
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Karolinska Institutet