Search: (WFRF:(Ramon Quiros J.)) srt2:(2005-2009) pers:(Chirlaque Maria Dolores) >
Glycosylated Hemogl...
Glycosylated Hemoglobin and Risk of Colorectal Cancer in Men and Women, the European Prospective Investigation into Cancer and Nutrition
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Rinaldi, Sabina (author)
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Rohrmann, Sabine (author)
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Jenab, Mazda (author)
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show more...
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Biessy, Carine (author)
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Sieri, Sabina (author)
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Palli, Domenico (author)
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Tumino, Rosario (author)
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Mattiello, Amalla (author)
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Vineis, Paolo (author)
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Nieters, Alexandra (author)
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Linseisen, Jakob (author)
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Pischon, Tobias (author)
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- Boeing, Heiner (author)
- Näringsforskning
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- Hallmans, Göran (author)
- Umeå universitet,Näringsforskning
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- Palmqvist, Richard (author)
- Umeå universitet,Patologi
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- Manjer, Jonas (author)
- Lund University,Lunds universitet,Kirurgi,Forskargrupper vid Lunds universitet,Surgery,Lund University Research Groups
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- Wirfält, Elisabet (author)
- Lund University,Lunds universitet,Nutritionsepidemiologi,Forskargrupper vid Lunds universitet,Nutrition Epidemiology,Lund University Research Groups
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Crowe, Francesca L. (author)
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Khaw, Kay-Tee T. (author)
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Bingham, Sheila (author)
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Tjonneland, Anne (author)
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Olsen, Anja (author)
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Overvad, Kim (author)
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Lund, Eiliv (author)
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Skeie, Guri (author)
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Clavel-Chapelon, Francoise (author)
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Boutron-Ruault, Marie-Christine (author)
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de lauzon-Guillain, Blandine (author)
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Ardanaz, Eva (author)
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Jakszyn, Paula (author)
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Quiros, Jose Ramon (author)
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Chirlaque, Maria-Dolores (author)
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Sanchez, Maria-Jose (author)
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Dorronsoro, Miren (author)
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Trichopoulou, Antonia (author)
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LagioU, Pagona (author)
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Trichopouios, Dimitrious (author)
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Bueno-De-Mesquita, H. Bas (author)
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van Duijnhoven, Franzel J. B. (author)
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Peeters, Petra H. M. (author)
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Slimani, Nadia (author)
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Ferrari, Pietro (author)
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Byrnes, Graham B. (author)
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Riboli, Elio (author)
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Kaaks, Rudolf (author)
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(creator_code:org_t)
- 2008
- 2008
- English.
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In: Cancer Epidemiology Biomarkers & Prevention. - 1538-7755 .- 1055-9965. ; 17:11, s. 3108-3115
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http://dx.doi.org/10... (free)
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http://www.ncbi.nlm....
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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Abstract
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- Although large-scale prospective cohort studies have related hyperglycemia to increased risk of cancer overall, studies specifically on colorectal cancer have been generally small. We investigated the association between prediagnostic levels of glycosylated hemoglobin (HbA1c), a marker for average glucose level in blood, and colorectal cancer risk in a case-control study nested within the European Prospective Investigation into Cancer and Nutrition cohort. One thousand and twenty-six incident colorectal cancer cases (561 men and 465 women) and 1,026 matched controls were eligible for the study. Multivariate conditional logistic regression was used to estimate odds ratios (ORS) adjusted for possible confounders. Increasing HbA1c percentages were statistically significantly associated with a mild increase in colorectal cancer risk in the whole population [OR, 1.10; 95% confidence interval (CI), 1.01,1.19 for a 10% increase in HbA1c]. In women, increasing HbA1c percentages were associated with a statistically significant increase in colorectal cancer risk (OR, 1.16; 95% CI, 1.01, 1.32 for a 10% increase in HbA1c) and with a borderline statistically significant increase in rectum cancer (OR, 1.22; 95% CI, 0.99,1.50 for a 10% increase in HbA1c). No significant association with cancer risk was observed in men. The results of the current study suggest a mild implication of hyperglycemia in colorectal cancer, which seems more important in women than in men, and more for cancer of the rectum than of the colon. (Cancer Epidemiol Biomarkers Prev 2008;17(11):3108-15)
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Publication and Content Type
- art (subject category)
- ref (subject category)
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- By the author/editor
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Rinaldi, Sabina
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Rohrmann, Sabine
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Jenab, Mazda
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Biessy, Carine
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Sieri, Sabina
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Palli, Domenico
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show more...
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Tumino, Rosario
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Mattiello, Amall ...
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Vineis, Paolo
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Nieters, Alexand ...
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Linseisen, Jakob
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Pischon, Tobias
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Boeing, Heiner
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Hallmans, Göran
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Palmqvist, Richa ...
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Manjer, Jonas
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Wirfält, Elisabe ...
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Crowe, Francesca ...
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Khaw, Kay-Tee T.
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Bingham, Sheila
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Tjonneland, Anne
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Olsen, Anja
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Overvad, Kim
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Lund, Eiliv
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Skeie, Guri
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Clavel-Chapelon, ...
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Boutron-Ruault, ...
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de lauzon-Guilla ...
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Ardanaz, Eva
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Jakszyn, Paula
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Quiros, Jose Ram ...
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Chirlaque, Maria ...
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Sanchez, Maria-J ...
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Dorronsoro, Mire ...
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Trichopoulou, An ...
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LagioU, Pagona
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Trichopouios, Di ...
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Bueno-De-Mesquit ...
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van Duijnhoven, ...
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Peeters, Petra H ...
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Slimani, Nadia
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Ferrari, Pietro
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Byrnes, Graham B ...
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Riboli, Elio
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Kaaks, Rudolf
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Cancer and Oncol ...
- Articles in the publication
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Cancer Epidemiol ...
- By the university
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Lund University
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Umeå University