WFRF:(Omling Erik)
Sökning: WFRF:(Omling Erik) > A Nationwide Cohort...
- Omling, ErikLund University,Lunds universitet,Barnkirurgi,Forskargrupper vid Lunds universitet,Pediatric surgery,Lund University Research Groups,Skåne University Hospital (författare)
A Nationwide Cohort Study of Outcome after Pediatric Appendicitis
- Artikel/kapitelEngelska2021
Förlag, utgivningsår, omfång ...
- 2020-06-26
- Georg Thieme Verlag KG,2021
Nummerbeteckningar
- LIBRIS-ID:oai:lup.lub.lu.se:95a0c8a1-0ccd-446a-a980-d7fdf02bd7ef
- https://lup.lub.lu.se/record/95a0c8a1-0ccd-446a-a980-d7fdf02bd7efURI
- https://doi.org/10.1055/s-0040-1712508DOI
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- Språk:engelska
- Sammanfattning på:engelska
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- Introduction Children with appendicitis often present with complicated disease. The aim of this study was to describe the clinical management of pediatric appendicitis, and to report how disease severity and operative modality are associated with short- and long-term risks of adverse outcome. Materials and Methods A nationwide retrospective cohort study of all Swedish children (<18 years) diagnosed with appendicitis, 2001 to 2014 (n = 38,939). Primary and secondary outcomes were length of stay, surgical site infections, readmissions, 30-day mortality, and long-term risk of surgery for small bowel obstruction (SBO). Implications of complicated disease and operative modality were assessed with adjustment for age, gender, and trends over time. Results Complicated appendicitis was associated with longer hospital stay (4 vs. 2 days, p < 0.001), increased risk of surgical site infection (5.9 vs. 2.3%, adjusted odds ratio [aOR]: 2.64 [95% confidence interval, CI: 2.18-3.18], p < 0.001), readmission (5.5 vs. 1.2, aOR: 4.74 [95% CI: 4.08-5.53], p < 0.001), as well as long-term risk of surgery for SBO (0.7 vs. 0.2%, adjusted hazard ratio [aHR]: 3.89 [95% CI: 2.61-5.78], p < 0.001). Intended laparoscopic approach was associated with reduced risk of surgical site infections (2.3 vs. 3.1%, aOR: 0.74 [95% CI: 0.62-0.89], p = 0.001), but no overall reduction in risk for SBO; however, successful laparoscopic appendectomy was associated with less SBO during follow-up compared with open appendectomy (aHR: 0.27 [95% CI: 0.11-0.63], p = 0.002). Conclusion Children treated for complicated appendicitis are at risk of substantial short- and long-term morbidities. Fewer surgical site infections were seen after intended laparoscopic appendectomy, compared with open appendectomy, also when converted procedures were accounted for.
Ämnesord och genrebeteckningar
- MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Pediatrik hsv//swe
- MEDICAL AND HEALTH SCIENCES Clinical Medicine Pediatrics hsv//eng
- MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Kirurgi hsv//swe
- MEDICAL AND HEALTH SCIENCES Clinical Medicine Surgery hsv//eng
- complications
- laparoscopic
- pediatric appendicitis
- small bowel obstruction
- surgical site infection
Biuppslag (personer, institutioner, konferenser, titlar ...)
- Salö, MartinLund University,Lunds universitet,Barnkirurgi,Forskargrupper vid Lunds universitet,Pediatric surgery,Lund University Research Groups,Skåne University Hospital(Swepub:lu)med-ms21 (författare)
- Saluja, SaurabhCornell University(Swepub:lu)sa8082sa (författare)
- Bergbrant, SannaLund University,Lunds universitet,Kirurgi och folkhälsa,Forskargrupper vid Lunds universitet,Surgery and public health,Lund University Research Groups(Swepub:lu)su2461be (författare)
- Olsson, LouiseLund University,Lunds universitet,Kirurgi och folkhälsa,Forskargrupper vid Lunds universitet,Surgery and public health,Lund University Research Groups(Swepub:lu)lo4608ol (författare)
- Björk, JonasLund University,Lunds universitet,Kirurgi och folkhälsa,Forskargrupper vid Lunds universitet,Surgery and public health,Lund University Research Groups,Skåne University Hospital(Swepub:lu)ymed-jbj (författare)
- Hagander, LarsLund University,Lunds universitet,Kirurgi och folkhälsa,Forskargrupper vid Lunds universitet,Surgery and public health,Lund University Research Groups,Skåne University Hospital(Swepub:lu)med-lhd (författare)
- BarnkirurgiForskargrupper vid Lunds universitet (creator_code:org_t)
Sammanhörande titlar
- Ingår i:European Journal of Pediatric Surgery: Georg Thieme Verlag KG31:2, s. 191-1980939-72481439-359X
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