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WFRF:(Thomas Mervyn G.)
 

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  • Møller, Morten HylanderUniversity of Copenhagen,Copenhagen University Hospital (författare)

Higher versus lower oxygenation targets in adult ICU patients : A rapid practice guideline

  • Artikel/kapitelEngelska2024

Förlag, utgivningsår, omfång ...

  • 2024
  • 9 s.

Nummerbeteckningar

  • LIBRIS-ID:oai:lup.lub.lu.se:97aecce1-75ff-4ff2-9257-cba46e5620a6
  • https://lup.lub.lu.se/record/97aecce1-75ff-4ff2-9257-cba46e5620a6URI
  • https://doi.org/10.1111/aas.14366DOI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

Ingår i deldatabas

Klassifikation

  • Ämneskategori:art swepub-publicationtype
  • Ämneskategori:ref swepub-contenttype

Anmärkningar

  • The aim of this Intensive Care Medicine Rapid Practice Guideline (ICM-RPG) was to provide evidence-based clinical guidance about the use of higher versus lower oxygenation targets for adult patients in the intensive care unit (ICU). The guideline panel comprised 27 international panelists, including content experts, ICU clinicians, methodologists, and patient representatives. We adhered to the methodology for trustworthy clinical practice guidelines, including the use of the Grading of Recommendations Assessment, Development, and Evaluation approach to assess the certainty of evidence, and used the Evidence-to-Decision framework to generate recommendations. A recently published updated systematic review and meta-analysis constituted the evidence base. Through teleconferences and web-based discussions, the panel provided input on the balance and magnitude of the desirable and undesirable effects, the certainty of evidence, patients' values and preferences, costs and resources, equity, feasibility, acceptability, and research priorities. The updated systematic review and meta-analysis included data from 17 randomized clinical trials with 10,248 participants. There was little to no difference between the use of higher versus lower oxygenation targets for all outcomes with available data, including all-cause mortality, serious adverse events, stroke, functional outcomes, cognition, and health-related quality of life (very low certainty of evidence). The panel felt that values and preferences, costs and resources, and equity favored the use of lower oxygenation targets. The ICM-RPG panel issued one conditional recommendation against the use of higher oxygenation targets: “We suggest against the routine use of higher oxygenation targets in adult ICU patients (conditional recommendation, very low certainty of evidence). Remark: an oxygenation target of SpO2 88%–92% or PaO2 8 kPa/60 mmHg is relevant and safe for most adult ICU patients.”.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Granholm, AndersUniversity of Copenhagen,Copenhagen University Hospital (författare)
  • Al Duhailib, ZainabKing Faisal Specialist Hospital and Research Centre (författare)
  • Alhazzani, WaleedMcMaster University,St Joseph’s Healthcare Hamilton (författare)
  • Belley-Cote, EmilieMcMaster University,Population Health Research Institute, Ontario (författare)
  • Oczkowski, SimonMcMaster University (författare)
  • Vijayaraghavan, Bharath Kumar TirupakuzhiThe George Institute for Global Health (författare)
  • Sjövall, FredrikLund University,Lunds universitet,Anestesiologi och intensivvård,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Mitokondriell Medicin,Forskargrupper vid Lunds universitet,Anesthesiology and Intensive Care,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Mitochondrial Medicine,Lund University Research Groups,Skåne University Hospital(Swepub:lu)expb-fsa (författare)
  • Butler, EthanUniversity of Sydney,Royal North Shore Hospital (författare)
  • Zampieri, Fernando G.University of Alberta,Alberta Health Services (författare)
  • Mac Sweeney, RobRoyal Victoria Hospital, Belfast (författare)
  • Derde, Lennie P.G.University Medical Center Utrecht (författare)
  • Ruzycki-Chadwick, AllyHamilton Health Sciences (författare)
  • Mer, Mervyn (författare)
  • Burns, Karen E.A.Saint Michael's Hospital,University of Toronto,McMaster University (författare)
  • Ergan, BegümDokuz Eylül University (författare)
  • Al-Fares, Abdulrahman (författare)
  • Sjoding, Michael W.University of Michigan (författare)
  • Valley, Thomas S.University of Michigan (författare)
  • Rasmussen, Bodil S.Aalborg University,Aalborg University Hospital (författare)
  • Schjørring, Olav L.Aalborg University Hospital,Aalborg University (författare)
  • Prescott, Hallie C.University of Michigan (författare)
  • University of CopenhagenCopenhagen University Hospital (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:Acta Anaesthesiologica Scandinavica68:3, s. 302-3100001-5172

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