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A series of case st...
A series of case studies illustrating the role of flow cytometry in the diagnostic work-up of myelodysplastic syndromes
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- Westers, Theresia M. (author)
- Academic Medical Center of University of Amsterdam (AMC)
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- Saft, Leonie (author)
- Karolinska Institutet
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- van der Velden, Vincent H.J. (author)
- Erasmus University Medical Center
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- te Marvelde, Jeroen G. (author)
- Erasmus University Medical Center
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- Dunlop, Alan (author)
- Royal Marsden Hospital, London,King's College Hospital
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- Ireland, Robin (author)
- King's College Hospital
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- Valent, Peter (author)
- Medical University of Vienna
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- Porwit, Anna (author)
- Lund University,Lunds universitet,Patologi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Pathology, Lund,Section V,Department of Clinical Sciences, Lund,Faculty of Medicine
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- Béné, Marie C. (author)
- Nantes University Hospital
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- van de Loosdrecht, Arjan A. (author)
- Academic Medical Center of University of Amsterdam (AMC)
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(creator_code:org_t)
- 2022-02-18
- 2023
- English.
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In: Cytometry Part B - Clinical Cytometry. - : Wiley. - 1552-4949 .- 1552-4957. ; 104:1, s. 87-97
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Abstract
Subject headings
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- Current guidelines recommend flow cytometric analysis as part of the diagnostic assessment of patients with cytopenia suspected for myelodysplastic syndrome. Herein we describe the complete work-up of six cases using multimodal integrated diagnostics. Flow cytometry assessments are illustrated by plots from conventional and more recent analysis tools. The cases demonstrate the added value of flow cytometry in case of hypocellular, poor quality, or ambiguous bone marrow cytomorphology. Moreover, they demonstrate how immunophenotyping results support clinical decision-making in inconclusive and clinically ‘difficult’ cases.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Hematologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Hematology (hsv//eng)
Keyword
- cytopenia
- dysplasia
- flow cytometry
- integrated diagnostics
- MDS
Publication and Content Type
- art (subject category)
- ref (subject category)
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