Search: (WFRF:(Wolf Bernhard)) srt2:(2005-2009) >
Sexual differentiat...
Sexual differentiation and development
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- Giwercman, Y. L. (author)
- Lund University,Lunds universitet,Molekylärgenetisk reproduktionsmedicin, Malmö,Forskargrupper vid Lunds universitet,Wallenberglaboratoriet, Malmö,Medicinska fakulteten,Molecular genetic reproductive medicine, Malmö,Lund University Research Groups,The Wallenberg Laboratory, Malmö,Faculty of Medicine,Skåne University Hospital
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- Nordenskjöld, A. (author)
- Karolinska University Hospital
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Schill, Wolf-Bernhard (editor)
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Comhaire, Frank H (editor)
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Hargreave, Timothy B (editor)
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(creator_code:org_t)
- 2006
- 2006
- English.
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In: Andrology for the Clinician. - 3540231714 - 9783540231714 ; , s. 266-272
- Related links:
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http://dx.doi.org/10...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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Abstract
Subject headings
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- Normal sexual differentiation requires complex molecular events to take place in a precise order, and even though much knowledge has been gained in recent decades, further research is still needed to understand the pathogenesis of different disorders of sexual differentiation. For the clinician who is confronted with a child with sexual ambiguity, it is most important not to guess the sex but to initiate a proper diagnostic procedure, preferably done by a specialist team. Diagnosis generally requires a thorough clinical examination of the child and careful family history taking. The further diagnostic procedure includes cytogenetic hormonal and mutational analyses before sex assignment. Advances in molecular genetics are continuously providing tools for the detection of genetic defects and the primary diagnosis of intersex disorders. These methods may also be applied to prenatal diagnosis and carrier identification.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Fysiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Physiology (hsv//eng)
Publication and Content Type
- kap (subject category)
- ref (subject category)
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