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Contemporary use of...
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Bhatt, Nikita R.Queen Elizabeth Hospital King’s Lynn
(författare)
Contemporary use of phytotherapy in patients with lower urinary tract symptoms due to benign prostatic hyperplasia : results from the EVOLUTION European registry
- Artikel/kapitelEngelska2021
Förlag, utgivningsår, omfång ...
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2020-10-16
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Springer Science and Business Media LLC,2021
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7 s.
Nummerbeteckningar
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LIBRIS-ID:oai:lup.lub.lu.se:9ebe2860-6858-4d60-afe0-709b92eb53c8
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https://lup.lub.lu.se/record/9ebe2860-6858-4d60-afe0-709b92eb53c8URI
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https://doi.org/10.1007/s00345-020-03480-wDOI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:art swepub-publicationtype
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Ämneskategori:ref swepub-contenttype
Anmärkningar
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Background: To use the European Association of Urology Research Foundation (EAURF) registry data to determine the proportion of contemporary Lower Urinary Tract Symptoms associated with Benign Prostatic Enlargement (LUTS/BPE) patients prescribed phytotherapy, and to determine their subjective quality of life and clinical progression responses. Methods: This was a prospective multicenter multinational observational registry study, conducted over 2 years. Men ≥ 50 years seeking LUTS/BPE were divided at baseline into two cohorts, presently/recently untreated patients (PUP) commencing pharmacotherapy at baseline and presently/recently treated patients (c-PTP) continuing previously received pharmacotherapy, with 24-month follow-up (FU). Results: Overall, 2175 patients were enrolled with 1838 analyzed. Of the PUP cohort (n = 575), 92 (16%) received phytotherapy and 65 (71%, n = 65/92) completed 24-month FU, with France prescribing 34% (n = 30/89) the highest proportion of phytotherapy among all LUTS/BPE medications. In the c-PTP group (n = 1263), only 69 (5%) patients were using phytotherapy, falling to n = 35/69 (51%) at 24-month FU (highest in France 20% (n = 43/210)). Though defined disease progression occurred in ≤ 20%, with only 1% proceeding to surgical intervention, in both groups, clinically meaningful improvement was lower and symptom persistence was higher in PUP but similar in the treated (c-PTP) patients on phytotherapy compared to the other LUTS/BPE medication. Conclusion: Low heterogeneous prescribing rates for phytotherapy were reported in both PUP and c-PTP cohorts over the 24-month FU. Although phytotherapy led to subjective improvements, healthcare practitioners should prescribe them with caution until higher quality evidence and guideline recommendations supporting its use are available.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Davis, Niall F.Royal College of Surgeons in Ireland,Beaumont Hospital, Dublin
(författare)
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Witjes, W. P.European Association of Urology, Research Foundation
(författare)
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Bjartell, A.Lund University,Lunds universitet,Urologisk cancerforskning, Malmö,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Urological cancer, Malmö,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Skåne University Hospital,European Association of Urology, Research Foundation(Swepub:lu)kir-abj
(författare)
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Caris, C.European Association of Urology, Research Foundation
(författare)
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Patel, A.European Association of Urology, Research Foundation
(författare)
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de la Taille, A.Assistance Publique des Hôpitaux de Paris
(författare)
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Speakman, MarkSomerset NHS Foundation Trust
(författare)
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Martínez-Piñeiro, LuisUniversity Hospital La Paz
(författare)
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Tubaro, A.Sant'Andrea Hospital,Sapienza University of Rome
(författare)
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Queen Elizabeth Hospital King’s LynnRoyal College of Surgeons in Ireland
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:World Journal of Urology: Springer Science and Business Media LLC39:7, s. 2661-26670724-49831433-8726
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