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European stroke org...
European stroke organisation (ESO) guideline on cerebral small vessel disease, part 2, lacunar ischaemic stroke
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- Wardlaw, Joanna M. (författare)
- University of Edinburgh
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- Chabriat, Hugues (författare)
- Lariboisière Hospital
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- de Leeuw, Frank Erik (författare)
- Radboud University Medical Center
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- Debette, Stéphanie (författare)
- University of Bordeaux,Centre Hospitalier Universitaire de Bordeaux
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- Dichgans, Martin (författare)
- German Center for Neurodegenerative Diseases (DZNE), Bonn,Munich Cluster for Systems Neurology,German Centre for Cardiovascular Research,University Hospital Munich
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- Doubal, Fergus (författare)
- University of Edinburgh
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- Jokinen, Hanna (författare)
- Helsinki University Central Hospital
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- Katsanos, Aristeidis H. (författare)
- Population Health Research Institute, Ontario
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- Ornello, Raffaele (författare)
- University of L'Aquila
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- Pantoni, Leonardo (författare)
- Luigi Sacco University Hospital
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- Pasi, Marco (författare)
- University Of Tours
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- Pavlovic, Aleksandra M. (författare)
- University of Belgrade
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- Rudilosso, Salvatore (författare)
- Hospital Clínic of Barcelona
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- Schmidt, Reinhold (författare)
- Medical University of Graz
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- Staals, Julie (författare)
- Maastricht University Medical Centre
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- Taylor-Rowan, Martin (författare)
- University of Glasgow
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- Hussain, Salman (författare)
- European Stroke Organisation
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- Lindgren, Arne G. (författare)
- Lund University,Lunds universitet,Neurologi, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Klinisk strokeforskning,Forskargrupper vid Lunds universitet,Neurology, Lund,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine,Clinical Stroke Research Group,Lund University Research Groups
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(creator_code:org_t)
- Engelska.
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Ingår i: European Stroke Journal. - 2396-9873.
- Relaterad länk:
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http://dx.doi.org/10... (free)
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- A quarter of ischaemic strokes are lacunar subtype, typically neurologically mild, usually resulting from intrinsic cerebral small vessel pathology, with risk factor profiles and outcome rates differing from other stroke subtypes. This European Stroke Organisation (ESO) guideline provides evidence-based recommendations to assist with clinical decisions about management of lacunar ischaemic stroke to prevent adverse clinical outcomes. The guideline was developed according to ESO standard operating procedures and Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) methodology. We addressed acute treatment (including progressive lacunar stroke) and secondary prevention in lacunar ischaemic stroke, and prioritised the interventions of thrombolysis, antiplatelet drugs, blood pressure lowering, lipid lowering, lifestyle, and other interventions and their potential effects on the clinical outcomes recurrent stroke, dependency, major adverse cardiovascular events, death, cognitive decline, mobility, gait, or mood disorders. We systematically reviewed the literature, assessed the evidence and where feasible formulated evidence-based recommendations, and expert concensus statements. We found little direct evidence, mostly of low quality. We recommend that patients with suspected acute lacunar ischaemic stroke receive intravenous alteplase, antiplatelet drugs and avoid blood pressure lowering according to current acute ischaemic stroke guidelines. For secondary prevention, we recommend single antiplatelet treatment long-term, blood pressure control, and lipid lowering according to current guidelines. We recommend smoking cessation, regular exercise, other healthy lifestyle modifications, and avoid obesity for general health benefits. We cannot make any recommendation concerning progressive stroke or other drugs. Large randomised controlled trials with clinically important endpoints, including cognitive endpoints, are a priority for lacunar ischaemic stroke.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Neurologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Neurology (hsv//eng)
Nyckelord
- alteplase
- antihypertensive
- antiplatelet
- Guideline
- lacunar stroke
- lipid lowering
- small vessel disease
- stroke
- systematic review
- thrombolysis
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
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Wardlaw, Joanna ...
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Chabriat, Hugues
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de Leeuw, Frank ...
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Debette, Stéphan ...
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Dichgans, Martin
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Doubal, Fergus
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visa fler...
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Jokinen, Hanna
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Katsanos, Ariste ...
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Ornello, Raffael ...
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Pantoni, Leonard ...
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Pasi, Marco
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Pavlovic, Aleksa ...
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Rudilosso, Salva ...
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Schmidt, Reinhol ...
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Staals, Julie
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Taylor-Rowan, Ma ...
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Hussain, Salman
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Lindgren, Arne G ...
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Neurologi
- Artiklar i publikationen
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European Stroke ...
- Av lärosätet
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Lunds universitet