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  • Biancari, FaustoUniversity of Helsinki,Helsinki University Central Hospital (author)

Inter-institutional analysis of the outcome after postcardiotomy veno-arterial extracorporeal membrane oxygenation

  • Article/chapterEnglish2024

Publisher, publication year, extent ...

  • 2024
  • 10 s.

Numbers

  • LIBRIS-ID:oai:lup.lub.lu.se:e0c37499-a938-4e56-81a1-805eb8271797
  • https://lup.lub.lu.se/record/e0c37499-a938-4e56-81a1-805eb8271797URI
  • https://doi.org/10.1177/03913988231214934DOI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:154348409URI

Supplementary language notes

  • Language:English
  • Summary in:English

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  • Subject category:art swepub-publicationtype
  • Subject category:ref swepub-contenttype

Notes

  • Introduction: Patients requiring postcardiotomy veno-arterial extracorporeal membrane oxygenation (V-A-ECMO) have a high risk of early mortality. In this analysis, we evaluated whether any interinstitutional difference exists in the results of postcardiotomy V-A-ECMO. Methods: Studies on postcardiotomy V-A-ECMO were identified through a systematic review for individual patient data (IPD) meta-analysis. Analysis of interinstitutional results was performed using direct standardization, estimation of observed/expected in-hospital mortality ratio and propensity score matching. Results: Systematic review of the literature yielded 31 studies. Data from 10 studies on 1269 patients treated at 25 hospitals were available for the present analysis. In-hospital mortality was 66.7%. The relative risk of in-hospital mortality was significantly higher in six hospitals. Observed versus expected in-hospital mortality ratio showed that four hospitals were outliers with significantly increased mortality rates, and one hospital had significantly lower in-hospital mortality rate. Participating hospitals were classified as underperforming and overperforming hospitals if their observed/expected in-hospital mortality was higher or lower than 1.0, respectively. Among 395 propensity score matched pairs, the overperforming hospitals had significantly lower in-hospital mortality (60.3% vs 71.4%, p = 0.001) than underperforming hospitals. Low annual volume of postcardiotomy V-A-ECMO tended to be predictive of poor outcome only when adjusted for patients’ risk profile. Conclusions: In-hospital mortality after postcardiotomy V-A-ECMO differed significantly between participating hospitals. These findings suggest that in many centers there is room for improvement of the results of postcardiotomy V-A-ECMO.

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Added entries (persons, corporate bodies, meetings, titles ...)

  • Mäkikallio, TimoUniversity of Helsinki (author)
  • Loforte, AntonioSt. Orsola-Malpighi University Hospital (author)
  • Kaserer, Alexander (author)
  • Ruggieri, Vito G.Robert Debré University Hospital,University Hospital Of Trieste (author)
  • Cho, Sung MinJohns Hopkins University School of Medicine (author)
  • Kang, Jin KookJohns Hopkins University School of Medicine (author)
  • Dalén, MagnusKarolinska Institutet,Karolinska University Hospital (author)
  • Welp, HenrykUniversity Hospital Münster (author)
  • Jónsson, KristjánSahlgrenska University Hospital (author)
  • Ragnarsson, SigurdurLund University,Lunds universitet,Thoraxkirurgi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Minimalinvasiv hjärtkirurgi vid hjärtklaffsjukdom,Forskargrupper vid Lunds universitet,Blödningsrubbningar och akut typ-A dissektion,Heparinbindande protein inom thoraxkirurgi,Thoracic Surgery,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Minimal invasive cardiac surgery in valvular heart disease,Lund University Research Groups,Bleeding disorders and acute typ-A dissection,Heparin bindning protein in cardiothoracic surgery(Swepub:lu)med-sdr (author)
  • Hernández Pérez, Francisco J.University Hospital Puerta de Hierro (author)
  • Gatti, GiuseppeUniversity Hospital Of Trieste (author)
  • Alkhamees, KhalidPrince Sultan Cardiac Center (author)
  • Fiore, AntonioHenri Mondor Hospital (author)
  • Lechiancole, AndreaUniversity Hospital of Udine (author)
  • Rosato, Stefano (author)
  • Spadaccio, CristianoMayo Clinic Minnesota (author)
  • Pettinari, MatteoHospital Oost-Limburg (author)
  • Perrotti, AndreaUniversity Hospital Jean Minjoz (author)
  • Sahli, Sebastian D. (author)
  • L’Acqua, CamillaIstituto Nazionale dei Tumori,Centro Cardiologico Monzino (author)
  • Arafat, Amr A.Tanta University,Prince Sultan Cardiac Center (author)
  • Albabtain, Monirah A.Prince Sultan Cardiac Center (author)
  • AlBarak, Mohammed M.Prince Sultan Cardiac Center (author)
  • Laimoud, MohamedCairo University (author)
  • Djordjevic, IlijaUniversity Hospital of Cologne (author)
  • Krasivskyi, IhorUniversity Hospital of Cologne (author)
  • Samalavicius, RobertasVilnius University (author)
  • Jankuviene, AgneVilnius University (author)
  • Alonso-Fernandez-Gatta, MartaUniversity Hospital of Salamanca,Carlos III Health Institute (author)
  • Wilhelm, Markus J.University Hospital of Zurich (author)
  • Juvonen, TatuHelsinki University Central Hospital,University of Oulu (author)
  • Mariscalco, GiovanniGlenfield Hospital (author)
  • University of HelsinkiHelsinki University Central Hospital (creator_code:org_t)

Related titles

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