Model-based Assessment of f-Wave Signal Quality in Patients with Atrial Fibrillation

Henriksson, MikaelLund University,Lunds universitet,Avdelningen för Biomedicinsk teknik,Institutionen för biomedicinsk teknik,Institutioner vid LTH,Lunds Tekniska Högskola,Department of Biomedical Engineering,Departments at LTH,Faculty of Engineering, LTH (author)

Objective: The detection and analysis of atrial fibrillation (AF) in the ECG is greatly influenced by signal quality. The present study proposes and evaluates a model-based f-wave signal quality index (SQI), denoted S, for use in the QRST-cancelled ECG signal. Methods: S is computed using a harmonic f-wave model, allowing for variation in frequency and amplitude. The properties of S are evaluated on both f-waves and P-waves using 378 12-lead ECGs, 1875 single-lead ECGs, and simulated signals. Results: S decreases monotonically when noise is added to f-wave signals, even for noise which overlaps spectrally with f-waves. Moreover, S is shown to be closely associated with the accuracy of AF frequency estimation, where S>0.3 implies accurate estimation. When S is used as a measure of f-wave presence, AF detection performance improves: the sensitivity increases from 97.0% to 98.1% and the specificity increases from 97.4% to 97.8% when compared to the reference detector. Conclusion: The proposed SQI represents a novel approach to assessing f-wave signal quality, as well as to determining whether f-waves are present. Significance: The use of S improves the detection of AF and benefits the analysis of noisy ECGs.

MEDICIN OCH HÄLSOVETENSKAP Medicinsk bioteknologi Biomedicinsk laboratorievetenskap/teknologi hsv//swe
MEDICAL AND HEALTH SCIENCES Medical Biotechnology Biomedical Laboratory Science/Technology hsv//eng
AF detection
Atrial fibrillation (AF)
Computational modeling
Detectors
ECG
Electrocardiography
Estimation
f-wave modeling
Frequency estimation
Harmonic analysis
Indexes
signal quality index (SQI)

Petrenas, AndriusKaunas University of Technology (author)
Marozas, VaidotasKaunas University of Technology (author)
Sandberg, FridaLund University,Lunds universitet,Electrocardiology Research Group - CIEL,Forskargrupper vid Lunds universitet,Lund University Research Groups(Swepub:lu)es-fni (author)
Sornmo, LeifLund University,Lunds universitet,Institutionen för elektro- och informationsteknik,Institutioner vid LTH,Lunds Tekniska Högskola,Department of Electrical and Information Technology,Departments at LTH,Faculty of Engineering, LTH(Swepub:lu)tde-lso (author)
Avdelningen för Biomedicinsk teknikInstitutionen för biomedicinsk teknik (creator_code:org_t)

By the author/editor: Henriksson, Mika ...; Petrenas, Andriu ...; Marozas, Vaidota ...; Sandberg, Frida; Sornmo, Leif

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Medical Biotechn ...; and Biomedical Labor ...

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