C-reactive protein in traditional melanesians on Kitava

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C-reactive protein in traditional melanesians on Kitava

Carrera-Bastos, Pedro (författare): Lund University,Lunds universitet,Allmänmedicin och klinisk epidemiologi,Forskargrupper vid Lunds universitet,Family Medicine and Clinical Epidemiology,Lund University Research Groups,Center for Primary Health Care Research, Lund University/Region Skåne, Skåne University Hospital, Jan Waldenströms gata 35, CRC, hus 28 plan 11, 205 02, Malmö, Sweden.

Fontes-Villalba, Maelán (författare): Lund University,Lunds universitet,Allmänmedicin och klinisk epidemiologi,Forskargrupper vid Lunds universitet,Family Medicine and Clinical Epidemiology,Lund University Research Groups,Center for Primary Health Care Research, Lund University/Region Skåne, Skåne University Hospital, Jan Waldenströms gata 35, CRC, hus 28 plan 11, 205 02, Malmö, Sweden.

Gurven, Michael (författare): Department of Anthropology, University of California, Santa Barbara, USA.

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Muskiet, Frits A.J. (författare): Department of Laboratory Medicine, University Medical Centre Groningen, University of Groningen, Groningen, Netherlands.,University Medical Center Groningen

Åkerfeldt, Torbjörn (författare): Uppsala universitet,Uppsala University,Uppsala University Hospital,Klinisk kemi

Lindblad, Ulf (författare): Gothenburg University,Göteborgs universitet,University of Gothenburg,School of Public Health and Community Medicine, University of Gothenburg, Gothenburg, Sweden.,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine

Råstam, Lennart (författare): Lund University,Lunds universitet,Allmänmedicin och samhällsmedicin,Forskargrupper vid Lunds universitet,Family Medicine and Community Medicine,Lund University Research Groups,Department of Clinical Sciences, Community Medicine, Lund University, Lund, Sweden.

Frostegård, Johan (författare): Karolinska Institutet,Karolinska Institute,MM, Unit of Immunology and Chronic Disease, Karolinska Institutet, Stockholm, Sweden.

Shapira, Yinon (författare): Rambam Medical Center,Department of Ophthalmology, Rambam Health Care Campus, Haifa, Israel.

Shoenfeld, Yehuda (författare): Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center (Affiliated To Tel-Aviv University), Tel-Hashomer, Israel.; IM Sechenov First Moscow State Med Univ, Minist Hlth Russian Federat, Sechenov Univ, St Petersburg, Russia,Tel-Aviv University,Sheba Medical Center

Granfeldt, Yvonne (författare): Lund University,Lunds universitet,Avdelningen för livsmedel och läkemedel,Institutionen för processteknik och tillämpad biovetenskap,Institutioner vid LTH,Lunds Tekniska Högskola,Division of Food and Pharma,Department of Process and Life Science Engineering,Departments at LTH,Faculty of Engineering, LTH,Department of Food Technology, Engineering and Nutrition, Lund University, Lund, Sweden

Sundquist, Kristina (författare): Lund University,Lunds universitet,Allmänmedicin och klinisk epidemiologi,Forskargrupper vid Lunds universitet,Family Medicine and Clinical Epidemiology,Lund University Research Groups,Center for Primary Health Care Research,Skåne University Hospital,Lund Univ Reg Skane, Skane Univ Hosp, Ctr Primary Hlth Care Res, CRC, Jan Waldenstroms Gata 35,Hus 28 Plan 11, S-20502 Malmö, Sweden

Jönsson, Tommy (författare): Lund University,Lunds universitet,Allmänmedicin och klinisk epidemiologi,Forskargrupper vid Lunds universitet,Family Medicine and Clinical Epidemiology,Lund University Research Groups,Center for Primary Health Care Research, Lund University/Region Skåne, Skåne University Hospital, Jan Waldenströms gata 35, CRC, hus 28 plan 11, 205 02, Malmö, Sweden.,Skåne University Hospital

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2020-12-17
2020
Engelska.
Ingår i: BMC Cardiovascular Disorders. - : Springer Science and Business Media LLC. - 1471-2261. ; 20:1

Relaterad länk:: http://dx.doi.org/10... (free); visa fler...; https://bmccardiovas...; https://doi.org/10.1...; https://uu.diva-port... (primary) (Raw object); https://lup.lub.lu.s...; https://doi.org/10.1...; https://urn.kb.se/re...; http://kipublication...; https://gup.ub.gu.se...; visa färre...

Tidskriftsartikel (refereegranskat)

Abstract Ämnesord

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Background: Population-based levels of the chronic low-grade systemic inflammation biomarker, C-reactive protein (CRP), vary widely among traditional populations, despite their apparent absence of chronic conditions associated with chronic low-grade systemic inflammation, such as type 2 diabetes, metabolic syndrome and cardiovascular disease. We have previously reported an apparent absence of aforementioned conditions amongst the traditional Melanesian horticulturalists of Kitava, Trobriand Islands, Papua New Guinea. Our objective in this study was to clarify associations between chronic low-grade systemic inflammation and chronic cardiometabolic conditions by measuring CRP in a Kitava population sample. For comparison purposes, CRP was also measured in Swedish controls matched for age and gender. Methods: Fasting levels of serum CRP were measured cross-sectionally in ≥ 40-year-old Kitavans (N = 79) and Swedish controls (N = 83). Results: CRP was lower for Kitavans compared to Swedish controls (Mdn 0.5 mg/L range 0.1—48 mg/L and Mdn 1.1 mg/L range 0.1—33 mg/L, respectively, r =.18 p =.02). Among Kitavans, there were small negative associations between lnCRP for CRP values < 10 and total, low-density lipoprotein (LDL) and non-high-density lipoprotein (non-HDL) cholesterol. Among Swedish controls, associations of lnCRP for CRP values < 10 were medium positive with weight, body mass index, waist circumference, hip circumference and waist-hip ratio and low positive with triglyceride, total cholesterol-HDL cholesterol ratio, triglyceride-HDL cholesterol ratio and serum insulin. Conclusions: Chronic low-grade systemic inflammation, measured as CRP, was lower among Kitavans compared to Swedish controls, indicating a lower and average cardiovascular risk, respectively, for these populations.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Klinisk laboratoriemedicin (hsv//swe)
MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Clinical Laboratory Medicine (hsv//eng)

Nyckelord

C-reactive protein
Cardiovascular risk
Traditional melanesians
C-reactive protein

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Av författaren/redakt...: Carrera-Bastos, ...; Fontes-Villalba, ...; Gurven, Michael; Muskiet, Frits A ...; Åkerfeldt, Torbj ...; Lindblad, Ulf; visa fler...; Råstam, Lennart; Frostegård, Joha ...; Shapira, Yinon; Shoenfeld, Yehud ...; Granfeldt, Yvonn ...; Sundquist, Krist ...; Jönsson, Tommy; visa färre...

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