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Serum osteocalcin l...
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Bergenfelz, ALund University,Lunds universitet,Kirurgi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Surgery (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine
(författare)
Serum osteocalcin levels do not change during rapidly induced hypercalcemia in healthy subjects
- Artikel/kapitelEngelska1992
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LIBRIS-ID:oai:lup.lub.lu.se:ad37d2bb-6034-4201-95a6-9b3d20bf95c8
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https://lup.lub.lu.se/record/ad37d2bb-6034-4201-95a6-9b3d20bf95c8URI
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https://doi.org/10.1159/000182277DOI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:art swepub-publicationtype
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Ämneskategori:ref swepub-contenttype
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Since osteocalcin has been suggested to play a role in calcium homeostasis, we investigated its serum levels in 6 healthy subjects during a rapid calcium infusion. Serum levels of intact parathyroid hormone (PTH), 25-hydroxyvitamin D [25-(OH) D3] and 1,25-dihydroxyvitamin D [1,25-(OH)2 D3] were also determined. The calcium infusion increased plasma-ionized calcium levels from 1.25 +/- 0.04 to 1.54 +/- 0.07 mmol/l at 30 min (p less than 0.05). Concomitantly, serum levels of intact PTH declined from 2.1 +/- 0.9 to 0.2 +/- 0.3 mmol/l (p less than 0.05). In contrast, serum osteocalcin levels did not change. Further, during calcium infusion, serum levels of 1,25-(OH)2 D3 decreased from 81 +/- 17 to 75 +/- 15 pmol/l (p less than 0.05) whereas serum levels of 25-(OH) D3 did not change. The results therefore suggest that calcium per se does not influence osteocalcin secretion.
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Ahrén, BLund University,Lunds universitet,Medicin, Lund,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Medicine, Lund,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)med-bah
(författare)
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Kirurgi, LundSektion V
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Hormone Research: S. Karger AG37:1-2, s. 29-320301-01631423-0046
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