SwePub
Sök i LIBRIS databas

  Utökad sökning

WFRF:(Varma Murali)
 

Sökning: WFRF:(Varma Murali) > International Socie...

  • van der Kwast, TheoPrincess Margaret Hospital University of Toronto (författare)

International Society of Urological Pathology Expert Opinion on Grading of Urothelial Carcinoma

  • Artikel/kapitelEngelska2022

Förlag, utgivningsår, omfång ...

  • Elsevier BV,2022

Nummerbeteckningar

  • LIBRIS-ID:oai:lup.lub.lu.se:b0be8c33-2889-486b-b87d-2d49844c4146
  • https://lup.lub.lu.se/record/b0be8c33-2889-486b-b87d-2d49844c4146URI
  • https://doi.org/10.1016/j.euf.2021.03.017DOI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

Ingår i deldatabas

Klassifikation

  • Ämneskategori:for swepub-publicationtype
  • Ämneskategori:ref swepub-contenttype

Anmärkningar

  • Context: Grading is the mainstay for treatment decisions for patients with non–muscle-invasive bladder cancer (NMIBC). Objective: To determine the requirements for an optimal grading system for NMIBC via expert opinion. Evidence acquisition: A multidisciplinary working group established by the International Society of Urological Pathology reviewed available clinical, histopathological, and molecular evidence for an optimal grading system for bladder cancer. Evidence synthesis: Bladder cancer grading is a continuum and five different grading systems based on historical grounds could be envisaged. Splitting of the World Health Organization (WHO) 2004 low-grade class for NMIBC lacks diagnostic reproducibility and molecular-genetic support, while showing little difference in progression rate. Subdividing the clinically heterogeneous WHO 2004 high-grade class for NMIBC into intermediate and high risk categories using the WHO 1973 grading is supported by both clinical and molecular-genetic findings. Grading criteria for the WHO 1973 scheme were detailed on the basis of literature findings and expert opinion. Conclusions: Splitting of the WHO 2004 high-grade category into WHO 1973 grade 2 and 3 subsets is recommended. Provision of more detailed histological criteria for the WHO 1973 grading might facilitate the general acceptance of a hybrid four-tiered grading system or—as a preferred option—a more reproducible three-tiered system distinguishing low-, intermediate (high)-, and high-grade NMIBC. Patient summary: Improvement of the current systems for grading bladder cancer may result in better informed treatment decisions for patients with bladder cancer. A three-tiered grading system for non–muscle invasive bladder cancer derived by splitting the heterogeneous World Health Organization (WHO) 2004 high-grade category into WHO 1973 grade 2 and 3 subsets is recommended, as this may result in more informed treatment decisions.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Liedberg, FredrikLund University,Lunds universitet,Urologi - blåscancer, Malmö,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Urology - urothelial cancer, Malmö,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Skåne University Hospital(Swepub:lu)urok-fli (författare)
  • Black, Peter C.University of British Columbia (författare)
  • Kamat, AshishUniversity of Texas MD Anderson Cancer Center (författare)
  • van Rhijn, Bas W.G.Antoni Van Leeuwenhoek Hospital (författare)
  • Algaba, FerranAutonomous University of Barcelona (författare)
  • Berman, David M.Queen's University at Kingston (författare)
  • Hartmann, ArndtFriedrich-Alexander University Erlangen-Nürnberg (författare)
  • Lopez-Beltran, AntonioUniversity of Córdoba, Spain (författare)
  • Samaratunga, HemamaliAquesta Uropathology,University of Queensland (författare)
  • Varma, MuraliUniversity Hospital of Wales (författare)
  • Cheng, LiangIndiana University (författare)
  • Princess Margaret Hospital University of TorontoUrologi - blåscancer, Malmö (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:European Urology Focus: Elsevier BV8:2, s. 438-4462405-4569

Internetlänk

Hitta via bibliotek

Till lärosätets databas

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy