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- Lindvall, OlleLund University,Lunds universitet,Neurologi, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Neurology, Lund,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine (author)
Stem cell therapy for human neurodegenerative disorders-how to make it work
- Article/chapterEnglish2004
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- 2004-07-01
- Springer Science and Business Media LLC,2004
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- LIBRIS-ID:oai:lup.lub.lu.se:b0f56740-b745-49a9-9a55-c002bc4a7f67
- https://lup.lub.lu.se/record/270728URI
- https://doi.org/10.1038/nm1064DOI
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- Language:English
- Summary in:English
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- Recent progress shows that neurons suitable for transplantation can be generated from stem cells in culture, and that the adult brain produces new neurons from its own stem cells in response to injury. These findings raise hope for the development of stem cell therapies in human neurodegenerative disorders. Before clinical trials are initiated, we need to know much more about how to control stem cell proliferation and differentiation into specific phenotypes, induce their integration into existing neural and synaptic circuits, and optimize functional recovery in animal models closely resembling the human disease.
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- Kokaia, ZaalLund University,Lunds universitet,Neurologi, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Neurology, Lund,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)neur-zko (author)
- Martinez-Serrano, A (author)
- Neurologi, LundSektion IV (creator_code:org_t)
Related titles
- In:Nature Reviews Neuroscience: Springer Science and Business Media LLC10:Suppl., s. 42-501471-003X
- In:Nature Medicine: Springer Science and Business Media LLC10:Suppl., s. 42-501078-89561546-170X
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