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  • Kalia, Lorraine V (author)

Clinical Correlations With Lewy Body Pathology in LRRK2-Related Parkinson Disease.

  • Article/chapterEnglish2015

Publisher, publication year, extent ...

  • American Medical Association (AMA),2015

Numbers

  • LIBRIS-ID:oai:lup.lub.lu.se:b22c57e8-d69a-41aa-ab8d-bbbd1398305b
  • https://lup.lub.lu.se/record/4816480URI
  • https://doi.org/10.1001/jamaneurol.2014.2704DOI

Supplementary language notes

  • Language:English
  • Summary in:English

Part of subdatabase

Classification

  • Subject category:art swepub-publicationtype
  • Subject category:ref swepub-contenttype

Notes

  • Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common cause of genetic Parkinson disease (PD) known to date. The clinical features of manifesting LRRK2 mutation carriers are generally indistinguishable from those of patients with sporadic PD. However, some PD cases associated with LRRK2 mutations lack Lewy bodies (LBs), a neuropathological hallmark of PD. We investigated whether the presence or absence of LBs correlates with different clinical features in LRRK2-related PD.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Lang, Anthony E (author)
  • Hazrati, Lili-Naz (author)
  • Fujioka, Shinsuke (author)
  • Wszolek, Zbigniew K (author)
  • Dickson, Dennis W (author)
  • Ross, Owen A (author)
  • Van Deerlin, Vivianna M (author)
  • Trojanowski, John Q (author)
  • Hurtig, Howard I (author)
  • Alcalay, Roy N (author)
  • Marder, Karen S (author)
  • Clark, Lorraine N (author)
  • Gaig, Carles (author)
  • Tolosa, Eduardo (author)
  • Ruiz-Martínez, Javier (author)
  • Marti-Masso, Jose F (author)
  • Ferrer, Isidre (author)
  • López de Munain, Adolfo (author)
  • Goldman, Samuel M (author)
  • Schüle, Birgitt (author)
  • Langston, J William (author)
  • Aasly, Jan O (author)
  • Giordana, Maria T (author)
  • Bonifati, Vincenzo (author)
  • Puschmann, AndreasLund University,Lunds universitet,Neurologi, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Klinisk neurogenetik,Forskargrupper vid Lunds universitet,Neurology, Lund,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine,Clinical Neurogenetics,Lund University Research Groups,Skåne University Hospital(Swepub:lu)med-aps (author)
  • Canesi, Margherita (author)
  • Pezzoli, Gianni (author)
  • Maues De Paula, Andre (author)
  • Hasegawa, Kazuko (author)
  • Duyckaerts, Charles (author)
  • Brice, Alexis (author)
  • Stoessl, A Jon (author)
  • Marras, Connie (author)
  • Neurologi, LundSektion IV (creator_code:org_t)

Related titles

  • In:JAMA Neurology: American Medical Association (AMA)72:1, s. 100-1052168-61572168-6149

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