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- Inoue T, T (author)
Autofluorescence imaging videoendoscopy in the diagnosis of chronic atrophic fundal gastritis
- Article/chapterEnglish2010
Publisher, publication year, extent ...
- 2009-10-30
- Springer Science and Business Media LLC,2010
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- LIBRIS-ID:oai:lup.lub.lu.se:b3cea1e8-26a1-4be2-addc-9200da71f5f1
- https://lup.lub.lu.se/record/1542396URI
- https://doi.org/10.1007/s00535-009-0150-7DOI
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- Language:English
- Summary in:English
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- SwePubSwePub
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- Purpose: Diagnosis of chronic atrophic fundal gastritis (CAFG) is important to understand the pathogenesis of gastric diseases and assess the risk of gastric cancer. Autofluorescence imaging videoendoscopy (AFI) may enable the detection of mucosal features not apparent by conventional white-light endoscopy. The purpose of this study was to estimate the diagnostic ability of AFI in CAFG. Methods: A total of 77 patients were enrolled. Images of the gastric body in AFI and white-light mode were taken to assess the extent of gastritis, and biopsies were taken from green (n = 119) and purple (n = 146) mucosa in AFI images. The diagnostic accuracy of green mucosa for CAFG was investigated according to the Sydney system. Results: In per-patient analysis, the accuracy of green mucosa in patients with activity, inflammation, atrophy and intestinal metaplasia was 64, 93, 88 and 81%, respectively. In per-biopsy analysis, the accuracy for activity, inflammation, atrophy and intestinal metaplasia was 55, 62, 76 and 76%, respectively. Green areas in the gastric body exhibited more inflammation (p\0.001), atrophy (p\0.001) and intestinal metaplasia (p\0.001), whereas purple areas rarely contained atrophy or intestinal metaplasia. The kappa statistics for inter- and intra-observer agreement of AFI on assessing the extent of CAFG were 0.66 and 0.47, while those for white-light endoscopy were 0.56 and 0.39. Conclusions: AFI could diagnose the extent of CAFG as a green area in the gastric body, with higher reproducibility compared with white-light endoscopy. Therefore, AFI may be a useful adjunct to endoscopy to identify patients at high risk of developing gastric cancer.
Subject headings and genre
- MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin hsv//swe
- MEDICAL AND HEALTH SCIENCES Clinical Medicine hsv//eng
- Image-enhanced endoscopy
- Autofluorescence endoscopy
- Helicobacter pylori
- Atrophic gastritis
Added entries (persons, corporate bodies, meetings, titles ...)
- Uedo, N (author)
- Ishihara, R (author)
- Kawaguchi, T (author)
- Kawada, N (author)
- Chatani, R (author)
- Kizu, T (author)
- Tamai, C (author)
- Takeuchi, J (author)
- Higashino, K (author)
- Iishi, H (author)
- Tatsuta, M (author)
- Tomita, Y (author)
- Toth, ErvinLund University,Lunds universitet,Institutionen för kliniska vetenskaper, Malmö,Medicinska fakulteten,Department of Clinical Sciences, Malmö,Faculty of Medicine(Swepub:lu)ront-eto (author)
- Institutionen för kliniska vetenskaper, MalmöMedicinska fakulteten (creator_code:org_t)
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- In:Journal of Gastroenterology: Springer Science and Business Media LLC45:1, s. 45-510944-11741435-5922
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- Tamai, C
- Takeuchi, J
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