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  • Gu, YeqingPeking Union Medical College (författare)

Consumption of ultraprocessed food and development of chronic kidney disease : the Tianjin Chronic Low-Grade Systemic Inflammation and Health and UK Biobank Cohort Studies

  • Artikel/kapitelEngelska2023

Förlag, utgivningsår, omfång ...

  • Elsevier BV,2023

Nummerbeteckningar

  • LIBRIS-ID:oai:lup.lub.lu.se:b542123f-4c27-423c-8bf5-8865224c13af
  • https://lup.lub.lu.se/record/b542123f-4c27-423c-8bf5-8865224c13afURI
  • https://doi.org/10.1016/j.ajcnut.2022.11.005DOI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

Ingår i deldatabas

Klassifikation

  • Ämneskategori:art swepub-publicationtype
  • Ämneskategori:ref swepub-contenttype

Anmärkningar

  • BackgroundMany ultraprocessed food (UPF)-derived by-products may play a role in the development of chronic kidney disease (CKD). Although several studies have assessed the association of UPFs with kidney function decline or CKD in various countries, no evidence has been shown in China and the United Kingdom.ObjectivesThis study aims to evaluate the association between UPF consumption and risk of CKD in 2 large cohort studies from China and the United Kingdom.MethodsIn total, 23,775 and 102,332 participants without baseline CKD were enrolled in the Tianjin Chronic Low-Grade Systemic Inflammation and Health (TCLSIH) and UK Biobank cohort studies, respectively. Information on UPF consumption was obtained from a validated food frequency questionnaire in the TCLSIH and 24-h dietary recalls in the UK Biobank cohort. CKD was defined as an estimated glomerular filtration rate of ResultsAfter a median follow-up of 4.0 and 10.1 y, the incidence rates of CKD were around 1.1% and 1.7% in the TCLSIH and UK Biobank cohorts, respectively. The multivariable hazard ratio [95% confidence interval] of CKD across increasing quartiles (quartiles 1–4) of UPF consumption were 1 (reference), 1.24 (0.89, 1.72), 1.30 (0.91, 1.87), and 1.58 (1.07, 2.34) (P for trend = 0.02) in the TCLSIH cohort and 1 (reference), 1.14 (1.00, 1.31), 1.16 (1.01, 1.33), and 1.25 (1.09, 1.43) (P for trend < 0.01) in the UK Biobank cohort, respectively.ConclusionsOur finding indicated that higher UPF consumption is associated with a higher risk of CKD. Moreover, restricting UPF consumption may potentially benefit the prevention of CKD. Further clinical trials are required to clarify the causality.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Li, HuipingTianjin Medical University(Swepub:lu)hu0881li (författare)
  • Ma, HaoTulane University (författare)
  • Zhang, ShunmingTianjin Medical University(Swepub:lu)sh0215zh (författare)
  • Meng, GeTianjin Medical University (författare)
  • Zhang, QingTianjin Medical University General Hospital (författare)
  • Liu, LiTianjin Medical University General Hospital (författare)
  • Wu, HongmeiTianjin Medical University (författare)
  • Zhang, TingjingTianjin Medical University (författare)
  • Wang, XuenaTianjin Medical University (författare)
  • Zhang, JuanjuanTianjin Medical University (författare)
  • Sun, ShaomeiTianjin Medical University General Hospital (författare)
  • Wang, XingTianjin Medical University General Hospital (författare)
  • Zhou, MingTianjin Medical University General Hospital (författare)
  • Jia, Qiyu (författare)
  • Song, Kun (författare)
  • Liu, Qiang (författare)
  • Huang, Tao (författare)
  • Borné, YanLund University,Lunds universitet,Nutritionsepidemiologi,Forskargrupper vid Lunds universitet,Nutrition Epidemiology,Lund University Research Groups(Swepub:lu)med-boy (författare)
  • Wang, Yaogang (författare)
  • Qi, Lu (författare)
  • Niu, Kaijun (författare)
  • Peking Union Medical CollegeTianjin Medical University (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:The American journal of clinical nutrition: Elsevier BV117:2, s. 373-3821938-32070002-9165

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