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Potentially inappro...
Potentially inappropriate medication among people with dementia in eight European countries
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- Renom-Guiteras, Anna (författare)
- Autonomous University of Barcelona,Witten/Herdecke University
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- Thürmann, Petra A. (författare)
- HELIOS University Clinic Wuppertal,Witten/Herdecke University
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- Miralles, Ramón (författare)
- Autonomous University of Barcelona
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- Klaaßen-Mielke, Renate (författare)
- Ruhr-University Bochum
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- Thiem, Ulrich (författare)
- Elisabeth Hospital Essen,Ruhr-University Bochum
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- Stephan, Astrid (författare)
- Witten/Herdecke University,Martin-Luther-Universität Halle-Wittenberg
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- Bleijlevens, Michel H.C. (författare)
- Maastricht University
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- Jolley, David (författare)
- University of Manchester
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- Leino-Kilpi, Helena (författare)
- University of Turku
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- Saks, Kai (författare)
- University of Tartu
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- Soto-Martin, Maria (författare)
- National Institute for Health and Medical Research, France
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- Zabalegui, Adelaida (författare)
- Hospital Clínic of Barcelona,University of Barcelona
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- Meyer, Gabriele (författare)
- Witten/Herdecke University,Martin-Luther-Universität Halle-Wittenberg
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- Hallberg, Ingalill Rahm (creator_code:cre_t)
- Lund University,Lunds universitet,Pufendorfinstitutet,Universitetets särskilda verksamheter,Hälsofrämjande komplexa interventioner,Forskargrupper vid Lunds universitet,Pufendorf Institute for Advanced Studies,University Specialised Centres,Health-promoting Complex Interventions,Lund University Research Groups
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- Emilsson, Ulla Melin (creator_code:cre_t)
- Lund University,Lunds universitet,Socialhögskolan,Samhällsvetenskapliga institutioner och centrumbildningar,Samhällsvetenskapliga fakulteten,School of Social Work,Departments of Administrative, Economic and Social Sciences,Faculty of Social Sciences
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- Karlsson, Staffan (creator_code:cre_t)
- Lund University,Lunds universitet,Hälsofrämjande komplexa interventioner,Forskargrupper vid Lunds universitet,Health-promoting Complex Interventions,Lund University Research Groups
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- Lethin, Connie (creator_code:cre_t)
- Lund University,Lunds universitet,Klinisk minnesforskning,Forskargrupper vid Lunds universitet,Clinical Memory Research,Lund University Research Groups
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(creator_code:org_t)
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- 2017-09-01
- 2018
- Engelska 7 s.
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Ingår i: Age and Ageing. - : Oxford University Press (OUP). - 0002-0729 .- 1468-2834. ; 47:1, s. 68-74
- Relaterad länk:
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http://dx.doi.org/10... (free)
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https://academic.oup...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Objectives: to evaluate the frequency of potentially inappropriate medication (PIM) prescription among older people with dementia (PwD) from eight countries participating in the European study 'RightTimePlaceCare', and to evaluate factors and adverse outcomes associated with PIM prescription.Methods: survey of 2,004 PwD including a baseline assessment and follow-up after 3 months. Interviewers gathered data on age, sex, prescription of medication, cognitive status, functional status, comorbidity, setting and admission to hospital, fall-related injuries and mortality in the time between baseline and follow-up. The European Union(7)-PIM list was used to evaluate PIM prescription. Multivariate regression analysis was used to investigate factors and adverse outcomes associated with PIM prescription.Results: overall, 60% of the participants had at least one PIM prescription and 26.4% at least two. The PIM therapeutic subgroups most frequently prescribed were psycholeptics (26% of all PIM prescriptions) and 'drugs for acid-related disorders' (21%). PwD who were 80 years and older, lived in institutional long-term care settings, had higher comorbidity and were more functionally impaired were at higher risk of being prescribed two PIM or more. The prescription of two or more PIM was associated with higher chance of suffering from at least one fall-related injury and at least one episode of hospitalisation in the time between baseline and follow-up.Conclusions: PIM use among PwD is frequent and is associated with institutional long-term care, age, advanced morbidity and functional impairment. It also appears to be associated with adverse outcomes. Special attention should be paid to psycholeptics and drugs for acid-related disorders.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Geriatrik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Geriatrics (hsv//eng)
Nyckelord
- Aged
- Inappropriate prescribing
- Older people
- Potentially inappropriate medication list
- Proton-pump inhibitors
- Psychotropic drugs
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
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Renom-Guiteras, ...
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Thürmann, Petra ...
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Miralles, Ramón
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Klaaßen-Mielke, ...
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Thiem, Ulrich
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Stephan, Astrid
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Bleijlevens, Mic ...
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Jolley, David
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Leino-Kilpi, Hel ...
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Saks, Kai
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Soto-Martin, Mar ...
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Zabalegui, Adela ...
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Meyer, Gabriele
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Hallberg, Ingali ...
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Emilsson, Ulla M ...
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Karlsson, Staffa ...
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Lethin, Connie
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Age and Ageing
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