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Dosimetry-based tre...
Dosimetry-based treatment planning for molecular radiotherapy : A summary of the 2017 report from the Internal Dosimetry Task Force
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- Stokke, Caroline (författare)
- Oslo university hospital,Oslo Univ Hosp, Dept Diagnost Phys, Oslo, Norway.
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- Gabiña, Pablo Minguez (författare)
- Gurutzeta/Cruces University Hospital,Gurutzeta Cruces Univ Hosp, Dept Med Phys & Radiat Protect, Baracaldo, Spain.
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- Solný, Pavel (författare)
- Czech Technical University in Prague,Czech Tech Univ, Dept Dosimetry & Applicat Ionizing Radiat, Prague, Czech Republic.
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- Cicone, Francesco (författare)
- Sapienza University of Rome,Sapienza Univ Rome, St Andrea Hosp, Dept Surg & Med Sci & Translat Med, Nucl Med, Rome, Italy.
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- Sandström, Mattias (författare)
- Uppsala universitet,Uppsala University,Radiologi
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- Gleisner, Katarina Sjögreen (författare)
- Lund University,Lunds universitet,Nuclear Medicine Physics,Forskargrupper vid Lunds universitet,Lund University Research Groups,Lund Univ, Dept Med Radiat Phys, Clin Sci Lund, Lund, Sweden.
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- Chiesa, Carlo (författare)
- Istituto Nazionale dei Tumori,Fdn IRCCS Ist Nazl Tumori, Nucl Med Div, Milan, Italy.
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- Spezi, Emiliano (författare)
- Cardiff University,Cardiff Univ, Sch Engn, Cardiff, S Glam, Wales.
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- Paphiti, Maria (författare)
- Pammakaristos Hospital,Pammakaristos Hosp, Dept Med Phys, Athens, Greece.
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- Konijnenberg, Mark (författare)
- Erasmus University Medical Center,Erasmus MC, Dept Radiol & Nucl Med, Rotterdam, Netherlands.
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- Aldridge, Matt (författare)
- University College London,UCL Inst Nucl Med, Nucl Med Radiotherapy Phys, London, England.;UCL Hosp NHS Fdn Trust, London, England.
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- Tipping, Jill (författare)
- Christie NHS Foundation Trust,Christie NHS Fdn Trust, Nucl Med, Manchester, Lancs, England.
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- Wissmeyer, Michael (författare)
- Geneva University Hospital,Univ Hosp Geneva, Dept Nucl Med, Geneva, Switzerland.
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- Brans, Boudewijn (författare)
- Ghent University Hospital,Univ Hosp, Dept Nucl Med, Ghent, Belgium.;Univ Hosp, PET Ctr, Ghent, Belgium.
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- Bacher, Klaus (författare)
- Ghent University,Univ Ghent, Div Med Phys, Dept Basic Med Sci, Ghent, Belgium.
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- Kobe, Carsten (författare)
- University Hospital of Cologne,Univ Hosp Cologne, Dept Nucl Med, Cologne, Germany.
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- Flux, Glenn (författare)
- Institute of Cancer Research London,Royal Marsden Hospital, London,Royal Marsden Hosp, Joint Dept Phys, Sutton, Surrey, England.;Inst Canc Res, Sutton, Surrey, England.
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Oslo university hospital Oslo Univ Hosp, Dept Diagnost Phys, Oslo, Norway (creator_code:org_t)
- 2017-11-21
- 2017
- Engelska.
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Ingår i: EJNMMI Physics. - : Springer Science and Business Media LLC. - 2197-7364. ; 4:1
- Relaterad länk:
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http://dx.doi.org/10... (free)
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https://ejnmmiphys.s...
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https://doi.org/10.1...
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https://uu.diva-port... (primary) (Raw object)
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- Background: The European directive on basic safety standards (Council directive 2013/ 59 Euratom) mandates dosimetry-based treatment planning for radiopharmaceutical therapies. The directive comes into operation February 2018, and the aim of a report produced by the Internal Dosimetry Task Force of the European Association of Nuclear Medicine is to address this aspect of the directive. A summary of the report is presented. Results: A brief review of five of the most common therapy procedures is included in the current text, focused on the potential to perform patient-specific dosimetry. In the full report, 11 different therapeutic procedures are included, allowing additional considerations of effectiveness, references to specific literature on quantitative imaging and dosimetry, and existing evidence for absorbed dose-effect correlations for each treatment. Individualized treatment planning with tracer diagnostics and verification of the absorbed doses delivered following therapy is found to be scientifically feasible for almost all procedures investigated, using quantitative imaging and/or external monitoring. Translation of this directive into clinical practice will have significant implications for resource requirements. Conclusions: Molecular radiotherapy is undergoing a significant expansion, and the groundwork for dosimetry-based treatment planning is already in place. The mandated individualization is likely to improve the effectiveness of the treatments, although must be adequately resourced.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Radiologi och bildbehandling (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Radiology, Nuclear Medicine and Medical Imaging (hsv//eng)
- NATURVETENSKAP -- Fysik -- Annan fysik (hsv//swe)
- NATURAL SCIENCES -- Physical Sciences -- Other Physics Topics (hsv//eng)
Nyckelord
- Dosimetry
- Molecular radiotherapy
- Treatment planning
- Molecular radiotherapy
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Stokke, Caroline
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Gabiña, Pablo Mi ...
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Solný, Pavel
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Cicone, Francesc ...
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Sandström, Matti ...
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Gleisner, Katari ...
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Chiesa, Carlo
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Spezi, Emiliano
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Paphiti, Maria
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Konijnenberg, Ma ...
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Aldridge, Matt
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Tipping, Jill
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Wissmeyer, Micha ...
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Brans, Boudewijn
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Bacher, Klaus
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Kobe, Carsten
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Flux, Glenn
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Radiologi och bi ...
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NATURVETENSKAP
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och Fysik
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och Annan fysik
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EJNMMI Physics
- Av lärosätet
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Lunds universitet
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Uppsala universitet