Conclusiveness resolves the conflict between quality of evidence and imprecision in GRADE

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Anttila, StenSwedish Agency for Health Technology Assessment and Assessment of Social Services (författare)

Conclusiveness resolves the conflict between quality of evidence and imprecision in GRADE

Artikel/kapitelEngelska2016

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Elsevier BV,2016
5 s.
electronicrdacarrier

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LIBRIS-ID:oai:lup.lub.lu.se:c414e9cf-fc26-4f64-b42d-f4f9859f99c6
https://lup.lub.lu.se/record/c414e9cf-fc26-4f64-b42d-f4f9859f99c6URI
https://doi.org/10.1016/j.jclinepi.2016.03.019DOI

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Språk:engelska
Sammanfattning på:engelska &svenska

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Conclusiveness resolves the conflict between quality of evidence and imprecision in GRADE

Anmärkningar

The objective of our article is to show how “quality of evidence” and “imprecision,” as they are defined in Grading of Recommendations Assessment, Development, and Evaluation (GRADE) articles, may lead to confusion. We focus only on the context of systematic reviews.
ObjectivesThe objective of our article is to show how “quality of evidence” and “imprecision,” as they are defined in Grading of Recommendations Assessment, Development, and Evaluation (GRADE) articles, may lead to confusion. We focus only on the context of systematic reviews.Study Design and SettingWe analyze, with the aid of standard probabilistic and statistical concepts, the concepts of quality of evidence and imprecision as used in the GRADE framework. This enables us to point out some weaknesses in the relation between “quality of evidence” and “imprecision.”ResultsThe GRADE framework contains terms familiar from classical statistics, but these terms are used in nonstandard ways. Notably, “imprecision” does not have the meaning in the GRADE framework that it has in statistics, and the well-known table of “evidence levels” wrongly suggests that “quality of evidence” and “accuracy” express the same concept—they do not.ConclusionWe believe that “conclusiveness” rather than “imprecision” would be a suitable term to use when the question whether the CI excludes or includes certain critical margins is being addressed. Conclusiveness could also replace quality of evidence as the final step for a systematic reviewer.

Ämnesord och genrebeteckningar

MEDICIN OCH HÄLSOVETENSKAP Hälsovetenskap Medicinsk etik hsv//swe
MEDICAL AND HEALTH SCIENCES Health Sciences Medical Ethics hsv//eng
HUMANIORA Filosofi, etik och religion Filosofi hsv//swe
HUMANITIES Philosophy, Ethics and Religion Philosophy hsv//eng
GRADE
Imprecision
Conclusiveness
Accuracy
Confidence in estimate
Quality of evidence

Biuppslag (personer, institutioner, konferenser, titlar ...)

Persson, JohannesLund University,Lunds universitet,Teoretisk filosofi,Filosofiska institutionen,Institutioner,Humanistiska och teologiska fakulteterna,Theoretical Philosophy,Department of Philosophy,Departments,Joint Faculties of Humanities and Theology(Swepub:lu)fil-jpe (författare)
Vareman, NiklasLund University,Lunds universitet,Medicinsk etik,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Medical Ethics,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)fil-nva (författare)
Sahlin, Nils-EricLund University,Lunds universitet,Medicinsk etik,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Medical Ethics,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)fil-nes (författare)
Swedish Agency for Health Technology Assessment and Assessment of Social ServicesTeoretisk filosofi (creator_code:org_t)

Sammanhörande titlar

Ingår i:Journal of Clinical Epidemiology: Elsevier BV2016:75, s. 1-51878-59210895-4356

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Av författaren/redakt...: Anttila, Sten; Persson, Johanne ...; Vareman, Niklas; Sahlin, Nils-Eri ...

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MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Hälsovetenskap; och Medicinsk etik

HUMANIORA: HUMANIORA; och Filosofi etik oc ...; och Filosofi

Artiklar i publikationen: Journal of Clini ...

Av lärosätet: Lunds universitet

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