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Changes in T-Peak-t...
Changes in T-Peak-to-T-End Morphology Measured by Time-Warping are Associated with Ischemia-Induced Ventricular Fibrillation in a Porcine Model
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- Gomez, Neurys (författare)
- University of Zaragoza
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- Ramirez, Julia (författare)
- Queen Mary University,CIBER Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN),University of Zaragoza
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- Martin-Yebra, Alba (författare)
- University of Zaragoza,CIBER Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN)
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- Demidova, Marina M. (författare)
- Lund University,Lunds universitet,Kardiologi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Electrocardiology Research Group - CIEL,Forskargrupper vid Lunds universitet,Cardiology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund University Research Groups
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- Platonov, Pyotr (författare)
- Lund University,Lunds universitet,Kardiologi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Electrocardiology Research Group - CIEL,Forskargrupper vid Lunds universitet,Cardiology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund University Research Groups
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- Martinez, Juan Pablo (författare)
- CIBER Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN),University of Zaragoza
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- Laguna, Pablo (författare)
- CIBER Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN),University of Zaragoza
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(creator_code:org_t)
- 2023
- 2023
- Engelska.
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Ingår i: Computing in Cardiology, CinC 2023. - 2325-8861 .- 2325-887X. - 9798350382525
- Relaterad länk:
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http://dx.doi.org/10...
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https://lup.lub.lu.s...
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https://doi.org/10.2...
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Abstract
Ämnesord
Stäng
- In this work, we use a time-warping-based morphology variation index, d_{w}, computed between the peak and the end of the T-wave, and assess its association with the occurrence of ventricular fibrillation (VF) episodes in ischemic conditions. ECG recordings from 26 pigs under-going a 40-minute coronary occlusion were analyzed. The d_{w} series was obtained by quantifying the morphological differences between the final part of the T wave at different stages of the occlusion and a reference T wave in the control recording. During control recordings, d_{w} remained stationary with a median value along each recording of 1.76 ms, IQR of 1.80, while during artery occlusion followed a well-marked gradual increasing trend as ischemia progressed, with median of 15.47 ms, IQR of 18.53. At the 20-to-25 min period from occlusion onset (and during 5 min prior to VF episode) dw averages in the VF group was significantly higher than in the non-VF group with median values of 40.0 (and 34.4) vs 7.8 (and 7.7) ms, with p-values of 0.002 (and 0.001), respectively. In conclusion, dynamic increases of the d_{w} index during ischaemia progression in pigs are associated with VF occurrence.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Publikations- och innehållstyp
- kon (ämneskategori)
- ref (ämneskategori)
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