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Overweight, obesity...
Overweight, obesity and the risk of LADA : results from a Swedish case–control study and the Norwegian HUNT Study
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- Hjort, Rebecka (author)
- Karolinska Institutet,Karolinska Institute,Karolinska Inst, Inst Environm Med, Unit Epidemiol, Box 210, S-17177 Stockholm, Sweden
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- Ahlqvist, Emma (author)
- Lund University,Lunds universitet,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Genomics, Diabetes and Endocrinology,Lund University Research Groups,Lund Univ, Dept Clin Sci Malmo, Clin Res Ctr, Malmo, Sweden
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- Carlsson, Per-Ola (author)
- Uppsala universitet,Uppsala University,Transplantation och regenerativ medicin
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- Grill, Valdemar (author)
- St. Olav’s University Hospital,Norwegian University of Science and Technology,Norwegian Univ Sci & Technol, Dept Clin & Mol Med, NTNU, Trondheim, Norway;Trondheim Reg & Univ Hosp, St Olavs Hosp, Dept Endocrinol, Trondheim, Norway
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- Groop, Leif (author)
- University of Helsinki,Lund Univ, Dept Clin Sci Malmo, Clin Res Ctr, Malmo, Sweden;Univ Helsinki, Finnish Inst Mol Med, Helsinki, Finland
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- Martinell, Mats, 1971- (author)
- Uppsala universitet,Uppsala University,Allmänmedicin och preventivmedicin
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- Rasouli, Bahareh (author)
- Karolinska Institutet,Karolinska Institute,Karolinska Inst, Inst Environm Med, Unit Epidemiol, Box 210, S-17177 Stockholm, Sweden
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- Rosengren, Anders (author)
- Lund Univ, Dept Clin Sci Malmo, Clin Res Ctr, Malmo, Sweden
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- Tuomi, Tiinamaija (author)
- Folkhälsan Research Center,University of Helsinki,Helsinki University Central Hospital,Univ Helsinki, Helsinki Univ Hosp, Div Endocrinol, Abdominal Ctr,Res Program Diabet & Obes, Helsinki, Finland;Folkhalsan Res Ctr, Helsinki, Finland
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- Åsvold, Bjørn Olav (author)
- Norwegian University of Science and Technology,St. Olav’s University Hospital,Trondheim Reg & Univ Hosp, St Olavs Hosp, Dept Endocrinol, Trondheim, Norway;Norwegian Univ Sci & Technol, Dept Publ Hlth & Nursing, KG Jebsen Ctr Genet Epidemiol, NTNU, Trondheim, Norway
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- Carlsson, Sofia (author)
- Karolinska Institutet,Karolinska Institute,Karolinska Inst, Inst Environm Med, Unit Epidemiol, Box 210, S-17177 Stockholm, Sweden
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Alfredsson, L (author)
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(creator_code:org_t)
- 2018-03-27
- 2018
- English 11 s.
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In: Diabetologia. - : Springer Science and Business Media LLC. - 0012-186X .- 1432-0428. ; 61:6, s. 1333-1343
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Abstract
Subject headings
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- Aims/hypothesis: Excessive weight is a risk factor for type 2 diabetes, but its role in the promotion of autoimmune diabetes is not clear. We investigated the risk of latent autoimmune diabetes in adults (LADA) in relation to overweight/obesity in two large population-based studies. Methods: Analyses were based on incident cases of LADA (n = 425) and type 2 diabetes (n = 1420), and 1704 randomly selected control participants from a Swedish case–control study and prospective data from the Norwegian HUNT Study including 147 people with LADA and 1,012,957 person-years of follow-up (1984–2008). We present adjusted ORs and HRs with 95% CI. Results: In the Swedish data, obesity was associated with an increased risk of LADA (OR 2.93, 95% CI 2.17, 3.97), which was even stronger for type 2 diabetes (OR 18.88, 95% CI 14.29, 24.94). The association was stronger in LADA with low GAD antibody (GADA;
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Endokrinologi och diabetes (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Endocrinology and Diabetes (hsv//eng)
Keyword
- ANDIS
- ANDiU
- Body mass index
- Case–control study
- ESTRID
- HUNT Study
- LADA
- Latent autoimmune diabetes in adults
- Prospective study
- Type 2 diabetes
- diabetes
- diabetics
- ANDIS
Publication and Content Type
- art (subject category)
- ref (subject category)
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- By the author/editor
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Hjort, Rebecka
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Ahlqvist, Emma
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Carlsson, Per-Ol ...
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Grill, Valdemar
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Groop, Leif
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Martinell, Mats, ...
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Rasouli, Bahareh
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Rosengren, Ander ...
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Tuomi, Tiinamaij ...
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Åsvold, Bjørn Ol ...
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Carlsson, Sofia
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Alfredsson, L
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Endocrinology an ...
- Articles in the publication
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Diabetologia
- By the university
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Lund University
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Uppsala University
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Karolinska Institutet