Sökning: (WFRF:(Rossi Marco))
> (2020-2024) >
Coronary angiograph...
Coronary angiography- or fractional flow reserve-guided complete revascularization in multivessel disease STEMI : A Bayesian hierarchical network meta-analysis
-
- Archilletti, Federico (författare)
- Queen Mary University,University G.d'Annunzio of Chieti-Pescara
-
- Ricci, Fabrizio (författare)
- Lund University,Lunds universitet,Kardiovaskulär forskning - hypertoni,Forskargrupper vid Lunds universitet,Cardiovascular Research - Hypertension,Lund University Research Groups,Casa di Cura Villa Serena,University G.d'Annunzio of Chieti-Pescara
-
- Pelliccia, Francesco (författare)
- Sapienza University of Rome
-
visa fler...
-
- Dangas, George (författare)
- Icahn School of Medicine at Mount Sinai
-
Giuliani, Livio (författare)
-
- Radico, Francesco (författare)
- University G.d'Annunzio of Chieti-Pescara
-
Perfetti, Matteo (författare)
-
Rossi, Serena (författare)
-
- Gallina, Sabina (författare)
- University G.d'Annunzio of Chieti-Pescara
-
Maddestra, Nicola (författare)
-
- Khanji, Mohammed Y. (författare)
- Newham University Hospital,Barts Health NHS Trust,Queen Mary University
-
- Zimarino, Marco (författare)
- University G.d'Annunzio of Chieti-Pescara
-
visa färre...
-
Queen Mary University University Gd'Annunzio of Chieti-Pescara (creator_code:org_t)
- Elsevier BV, 2023
- 2023
- Engelska 7 s.
-
Ingår i: International Journal of Cardiology. - : Elsevier BV. - 0167-5273. ; 370, s. 122-128
- Relaterad länk:
-
http://dx.doi.org/10...
-
visa fler...
-
https://lup.lub.lu.s...
-
https://doi.org/10.1...
-
visa färre...
Abstract
Ämnesord
Stäng
- Aims: To identify the best strategy to achieve complete revascularization (CR) in patients with ST-elevation myocardial infarction (STEMI) and multi-vessel disease (MVD). Methods and results: We systematically reviewed the literature for randomized controlled trials (RCTs) comparing IRA-only PCI and CR guided by angiography or fractional flow reserve (FFR) in MVD-STEMI. Both frequentist (classical) and Bayesian network meta-analysis were performed, including a comparative hierarchy estimation of the probability to reduce the primary composite endpoint of all-cause death and new myocardial infarction (MI). We identified 11 RCTs, including 8193 STEMI patients. Compared with IRA-only strategy, CR significantly reduced the primary endpoint (OR: 0.73; 95%CI0.55–0.97). We observed non-significant difference between angiography and FFR guidance in reducing the primary endpoint (OR: 0.73, 95% CI 0.35–1.57). The Bayesian probability analysis ranked angio-guided CR as the best intervention yielding lowest risk of all-cause death or new MI (SUCRA92%). Conclusions: In patients with MVD-STEMI, CR is associated with a reduction in all-cause mortality and new MI compared with IRA-only PCI. Angio-guided CR is associated with the lowest risk of all-cause death or new MI, therefore the role of FFR-guidance in this setting is questionable. Condensed abstract: Both frequentist and Bayesian network meta-analysis were performed to compare infarct-related artery (IRA)-only percutaneous coronary intervention (PCI) and complete revascularization (CR) guided by angiography or fractional flow reserve (FFR) in multivessel disease (MVD) and acute ST-elevation myocardial infarction (STEMI). Eleven randomized controlled trials were identified, including 8193 STEMI patients. Compared with IRA-only strategy, CR significantly reduced the incidence of the composite endpoint of all-cause death and new myocardial infarction without significant difference in angio-guided and FFR-guided CR. The Bayesian probability analysis ranked angio-guided CR as the best intervention yielding lowest risk of the composite endpoint and, therefore the role of FFR-guidance in this setting is questionable.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Nyckelord
- Acute myocardial infarction
- Complete revascularization
- Percutaneous coronary intervention
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
-
Archilletti, Fed ...
-
Ricci, Fabrizio
-
Pelliccia, Franc ...
-
Dangas, George
-
Giuliani, Livio
-
Radico, Francesc ...
-
visa fler...
-
Perfetti, Matteo
-
Rossi, Serena
-
Gallina, Sabina
-
Maddestra, Nicol ...
-
Khanji, Mohammed ...
-
Zimarino, Marco
-
visa färre...
- Om ämnet
-
- MEDICIN OCH HÄLSOVETENSKAP
-
MEDICIN OCH HÄLS ...
-
och Klinisk medicin
-
och Kardiologi
- Artiklar i publikationen
-
International Jo ...
- Av lärosätet
-
Lunds universitet