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  • Betancourt, Lazaro HiramLund University,Lunds universitet,Clinical Protein Science and Imaging,Forskargrupper vid Lunds universitet,Lund University Research Groups (author)

The human melanoma proteome atlas-Defining the molecular pathology

  • Article/chapterEnglish2021

Publisher, publication year, extent ...

  • 2021-07-04
  • Wiley,2021

Numbers

  • LIBRIS-ID:oai:lup.lub.lu.se:d060c33f-1ec5-4816-b287-e05bbbb04504
  • https://lup.lub.lu.se/record/d060c33f-1ec5-4816-b287-e05bbbb04504URI
  • https://doi.org/10.1002/ctm2.473DOI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:147273329URI

Supplementary language notes

  • Language:English
  • Summary in:English

Part of subdatabase

Classification

  • Subject category:art swepub-publicationtype
  • Subject category:ref swepub-contenttype

Notes

  • The MM500 study is an initiative to map the protein levels in malignant melanoma tumor samples, focused on in-depth histopathology coupled to proteome characterization. The protein levels and localization were determined for a broad spectrum of diverse, surgically isolated melanoma tumors originating from multiple body locations. More than 15,500 proteoforms were identified by mass spectrometry, from which chromosomal and subcellular localization was annotated within both primary and metastatic melanoma. The data generated by global proteomic experiments covered 72% of the proteins identified in the recently reported high stringency blueprint of the human proteome. This study contributes to the NIH Cancer Moonshot initiative combining detailed histopathological presentation with the molecular characterization for 505 melanoma tumor samples, localized in 26 organs from 232 patients.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Gil, JeovanisLund University,Lunds universitet,Klinisk kemi, Malmö,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Clinical Chemistry, Malmö,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments(Swepub:lu)je2062gi (author)
  • Kim, YonghyoLund University,Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Biomarkörer och Epi,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Biomarkers and epidemiology,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)yo6042ki (author)
  • Doma, ViktóriaSemmelweis University (author)
  • Çakır, UğurSemmelweis University (author)
  • Sanchez, AnielLund University,Lunds universitet,Klinisk kemi, Malmö,Forskargrupper vid Lunds universitet,Clinical Protein Science and Imaging,Clinical Chemistry, Malmö,Lund University Research Groups,Skåne University Hospital(Swepub:lu)an3128sa (author)
  • Murillo, Jimmy RodriguezKarolinska Institutet (author)
  • Kuras, MagdalenaLund University,Lunds universitet,Klinisk kemi, Malmö,Forskargrupper vid Lunds universitet,Clinical Chemistry, Malmö,Lund University Research Groups,Skåne University Hospital(Swepub:lu)ma4830ku (author)
  • Parada, Indira PlaLund University,Lunds universitet,Klinisk kemi, Malmö,Forskargrupper vid Lunds universitet,Clinical Protein Science and Imaging,Clinical Chemistry, Malmö,Lund University Research Groups,Skåne University Hospital(Swepub:lu)in2411pl (author)
  • Sugihara, YutakaLund University,Lunds universitet,Clinical Protein Science and Imaging,Forskargrupper vid Lunds universitet,Lund University Research Groups(Swepub:lu)med-yas (author)
  • Appelqvist, RogerLund University,Lunds universitet,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Clinical Protein Science and Imaging,Forskargrupper vid Lunds universitet,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund University Research Groups(Swepub:lu)elma-rai (author)
  • Wieslander, ElisabetLund University,Lunds universitet,Clinical Protein Science and Imaging,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Biomarkörer och Epi,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Biomarkers and epidemiology,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)med-etw (author)
  • Welinder, CharlotteLund University,Lunds universitet,Masspektrometri,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,BioMS,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Biomarkörer och Epi,Sektion I,Institutionen för kliniska vetenskaper, Lund,Mass Spectrometry,Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Biomarkers and epidemiology,Section I,Department of Clinical Sciences, Lund(Swepub:lu)onk-cbr (author)
  • Velasquez, ErikaLund University,Lunds universitet,Klinisk kemi, Malmö,Forskargrupper vid Lunds universitet,Biomarkörer och Epi,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Clinical Chemistry, Malmö,Lund University Research Groups,Biomarkers and epidemiology,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital(Swepub:lu)er0360ve (author)
  • de Almeida, Natália PintoLund University,Lunds universitet,Biomarkörer och Epi,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Biomarkers and epidemiology,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine,Federal University of Rio de Janeiro(Swepub:lu)na7664pi (author)
  • Woldmar, NicoleLund University,Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Biomarkörer och Epi,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Biomarkers and epidemiology,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine,Federal University of Rio de Janeiro(Swepub:lu)ni5471wo (author)
  • Marko-Varga, MatildaLund University,Lunds universitet,Avdelningen för Biomedicinsk teknik,Institutionen för biomedicinsk teknik,Institutioner vid LTH,Lunds Tekniska Högskola,Department of Biomedical Engineering,Departments at LTH,Faculty of Engineering, LTH(Swepub:lu)ma7728ma (author)
  • Pawłowski, KrzysztofLund University,Lunds universitet,Klinisk kemi, Malmö,Forskargrupper vid Lunds universitet,Clinical Protein Science and Imaging,Clinical Chemistry, Malmö,Lund University Research Groups,University of Warsaw,Skåne University Hospital,University of Texas(Swepub:lu)med-kzp (author)
  • Eriksson, JonatanLund University,Lunds universitet,Clinical Protein Science and Imaging,Forskargrupper vid Lunds universitet,Lund University Research Groups(Swepub:lu)jo5130er (author)
  • Szeitz, BeátaSemmelweis University (author)
  • Baldetorp, BoLund University,Lunds universitet,BioMS,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments(Swepub:lu)onk-bba (author)
  • Ingvar, ChristianLund University,Lunds universitet,Lunds Melanomstudiegrupp,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Lund Melanoma Study Group,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Skåne University Hospital(Swepub:lu)kir-cin (author)
  • Olsson, HåkanLund University,Lunds universitet,Lunds Melanomstudiegrupp,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Lund Melanoma Study Group,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Skåne University Hospital(Swepub:lu)onk-hol (author)
  • Lundgren, LottaLund University,Lunds universitet,Medicinsk strålningsfysik, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Medical Radiation Physics, Lund,Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital(Swepub:lu)med-a-j (author)
  • Lindberg, HenrikLund University,Lunds universitet,Clinical Protein Science and Imaging,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments(Swepub:lu)elma-hkl (author)
  • Oskolas, HenriettLund University,Lunds universitet,Clinical Protein Science and Imaging,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments(Swepub:lu)med-hk- (author)
  • Lee, BoramLund University,Lunds universitet,Biomarkörer och Epi,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Biomarkers and epidemiology,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)bo8431le (author)
  • Berge, EthanLund University,Lunds universitet,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)et2176be (author)
  • Sjögren, MarieLund University,Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Biomarkörer och Epi,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Biomarkers and epidemiology,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)med-ms44 (author)
  • Eriksson, CarinaLund University,Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Biomarkörer och Epi,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Biomarkers and epidemiology,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)ca8381er (author)
  • Kim, DasolYonsei University(Swepub:lu)da5567ki (author)
  • Kwon, Ho JeongYonsei University(Swepub:lu)ho7625kw (author)
  • Knudsen, BeatriceUtah State University (author)
  • Rezeli, MelindaLund University,Lunds universitet,BioMS,Forskargrupper vid Lunds universitet,Clinical Protein Science and Imaging,Lund University Research Groups(Swepub:lu)elma-mrl (author)
  • Hong, RunyuNew York University (author)
  • Horvatovich, PeterUniversity of Groningen(Swepub:lu)pe4034ho (author)
  • Miliotis, TassoAstraZeneca, Sweden(Swepub:lu)med-tms (author)
  • Nishimura, ToshihideSt. Marianna University School of Medicine (author)
  • Kato, HarubumiTokyo Medical University (author)
  • Steinfelder, ErikThermo Fisher Scientific Inc. (author)
  • Oppermann, MadalinaThermo Fisher Scientific Inc. (author)
  • Miller, KenThermo Fisher Scientific Inc. (author)
  • Florindi, Francesco (author)
  • Zhou, QiminShanghai Jiao Tong University(Swepub:lu)qi5175zh (author)
  • Domont, Gilberto BFederal University of Rio de Janeiro (author)
  • Pizzatti, LucianaFederal University of Rio de Janeiro (author)
  • Nogueira, Fábio C.S.Federal University of Rio de Janeiro (author)
  • Horvath, PeterBiological Research Center Of The Hungarian Academy Of Sciences(Swepub:lu)pe2256ho (author)
  • Szadai, LeticiaUniversity of Szeged (author)
  • Timar, JozsefSemmelweis University (author)
  • Karpati, SaroltaSemmelweis University (author)
  • Szasz, A. MarcellSemmelweis University (author)
  • Malm, JohanLund University,Lunds universitet,Klinisk kemi, Malmö,Forskargrupper vid Lunds universitet,Clinical Protein Science and Imaging,Clinical Chemistry, Malmö,Lund University Research Groups,Skåne University Hospital(Swepub:lu)klke-jma (author)
  • Fenyö, DavidNew York University (author)
  • Ekedahl, HenrikLund University,Lunds universitet,Lymfom - Klinisk forskning,Forskargrupper vid Lunds universitet,Lymphoma - Clinical Research,Lund University Research Groups,Skåne University Hospital(Swepub:lu)med-hie (author)
  • Németh, István BalázsUniversity of Szeged (author)
  • Marko-Varga, GyörgyLund University,Lunds universitet,Clinical Protein Science and Imaging,Forskargrupper vid Lunds universitet,Lund University Research Groups,Yonsei University,Tokyo Medical University(Swepub:lu)akem-gmv (author)
  • Clinical Protein Science and ImagingForskargrupper vid Lunds universitet (creator_code:org_t)

Related titles

  • In:Clinical and Translational Medicine: Wiley11:7, s. 1-202001-1326

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