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A longitudinal coho...
A longitudinal cohort study on the prevalence of Helicobacter pylori antibodies in Swedish children and adolescents.
- Article/chapterEnglish2002
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LIBRIS-ID:oai:lup.lub.lu.se:d6b92d14-a8e8-47ba-887a-e73f24dc4299
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https://lup.lub.lu.se/record/109755URI
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https://doi.org/10.1080/080352502760069025DOI
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Language:English
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Summary in:English
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The aim of this study was to monitor the Helicobacter pylori antibody seroprevalence of an asymptomatic cohort between the ages of 4 and 18 y. The H. pylori antibody titres in a longitudinally followed cohort of 168 native Swedish children (born between 1972 and 1974) were established at 4, 8, 12, 16, and 18 y of age. Seventeen children (10.1%) were found positive on at least one occasion when a paediatric cut-off was applied. Five children (3.0%) reached levels considered positive in adults. The seroprevalence at 4 y of age was 4.0%, at 8 y 2.5%, at 12 y 4.9%, at 16 y 5.3%, and at 18 y 6.3%. The difference in serological titres between the age groups was not significant. A change from negative to positive after the age of 4 took place in 5 of the cases. Spontaneous seroreversion appeared in 5 cases. CONCLUSION: Our findings showed no significant differences among the various age groups. Seventeen of the 168 children (10.1%) had been infected at some time, the prevalence ranging from 2.5% to 6.3%. Seroconversion and seroreversion occurred infrequently between the ages of 4 and 18 y.
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Bredberg, A
(author)
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Sveger, TomasLund University,Lunds universitet,Preventiv pediatrik,Forskargrupper vid Lunds universitet,Preventive Paediatrics,Lund University Research Groups(Swepub:lu)pedi-tsv
(author)
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Axelsson, IreneLund University,Lunds universitet,Pediatrik, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Paediatrics (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)pedi-iax
(author)
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Preventiv pediatrikForskargrupper vid Lunds universitet
(creator_code:org_t)
Related titles
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In:Acta Pædiatrica91:6, s. 636-6401651-2227
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