SwePub
Sök i LIBRIS databas

  Extended search

WFRF:(Törnqvist Anna Lena)
 

Search: WFRF:(Törnqvist Anna Lena) > Long-Term Effects o...

  • Volkmann, Jens (author)

Long-Term Effects of Pallidal or Subthalamic Deep Brain Stimulation on Quality of Life in Parkinson's Disease

  • Article/chapterEnglish2009

Publisher, publication year, extent ...

  • 2009-05-01
  • Wiley,2009

Numbers

  • LIBRIS-ID:oai:lup.lub.lu.se:db6bc797-0dee-46fc-ba25-d60f7e2eb046
  • https://lup.lub.lu.se/record/1462974URI
  • https://doi.org/10.1002/mds.22496DOI

Supplementary language notes

  • Language:English
  • Summary in:English

Part of subdatabase

Classification

  • Subject category:art swepub-publicationtype
  • Subject category:ref swepub-contenttype

Notes

  • We assessed the effects of deep brain stimulation of the subthalamic nucleus (STN-DBS) or internal pallidum (GPi-DBS) on health-related quality of life (HrQoL) in patients with advanced Parkinson's disease participating in a previously reported multicenter trial. Sickness Impact Profile (SIP) questionnaires were available for analysis in a Subgroup of n = 20/20 patients with GPi-DBS and n = 45/49 patients with STN-DBS at baseline, 6 and 36 months. The SIP provides a physical dimension and a psychosocial dimension sum score and 12 category scores: Alertness/Intellectual Behavior (AIB), Ambulation (A), Body Care and Movement (BCM), Communication (C), Eating (E), Emotional Behavior (EB), Home Management (HM), Mobility (M), Recreation and Pastimes (RP), Sleep and Rest (SR), Social Interaction (SI), and Work (W). Motor functioning was assessed by means of the Unified Parkinson's Disease Rating Scale and diaries. At 6 months significant improvements in off-period motor symptoms and activities of daily living were paralleled by significant reductions in the total, physical, and psychosocial SIP score in both treatment groups. At 3 years, sustained improvements were observed in the physical dimension score, BCM, E, M, RP after STN-DBS and M, SI after GPi-DBS. All other SIP subscores approached baseline values, but were still the same or better (except C) whereas motor functioning remained stable after 36 months. STN-DBS and GPi-DBS led to significant early improvements in HrQoL. Despite sustained motor improvements many of these initial benefits were lost after 3 years. This may reflect either progression of the disease or adaptive changes in the subjective perception of health-related wellbeing over time. (C) 2009 Movement Disorder Society

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Albanese, Alberto (author)
  • Kulisevsky, Jaime (author)
  • Törnqvist, Anna LenaLund University,Lunds universitet,Neurokirurgi,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Neurosurgery,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)neur-ato (author)
  • Houeto, Jean-Luc (author)
  • Pidoux, Bernard (author)
  • Bonnet, Anne-Marie (author)
  • Mendes, Alexandre (author)
  • Benabid, Alim-Louis (author)
  • Fraix, Valerie (author)
  • Van Blercom, Nadege (author)
  • Xie, Jing (author)
  • Obeso, Jose (author)
  • Cruz Rodriguez-Oroz, Maria (author)
  • Guridi, Jurge (author)
  • Schnitzler, Alfons (author)
  • Timmermann, Lars (author)
  • Gironell, Alexandre A. (author)
  • Molet, Juan (author)
  • Pascual-Sedano, Benta (author)
  • Rehncrona, StigLund University,Lunds universitet,Neurokirurgi,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Neurosurgery,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)nkir-sre (author)
  • Moro, Elena (author)
  • Lang, Anthony C. (author)
  • Lozano, Andres M. (author)
  • Bentivoglio, Anna Rita (author)
  • Scerrati, Massimo (author)
  • Contarino, Maria Fiorella (author)
  • Romito, Luigi (author)
  • Janssens, Marc (author)
  • Agid, Yves (author)
  • NeurokirurgiSektion IV (creator_code:org_t)

Related titles

  • In:Movement Disorders: Wiley24:8, s. 1154-11610885-3185

Internet link

Find in a library

To the university's database

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Close

Copy and save the link in order to return to this view