id:"swepub:oai:lup.lub.lu.se:ddf71569-f10f-4c34-aa2f-2c1083d4e241"
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- Fransson, HelenLund University,Lunds universitet,Klinisk fysiologi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Matematik LTH,Matematikcentrum,Institutioner vid LTH,Lunds Tekniska Högskola,Clinical Physiology (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Mathematics (Faculty of Engineering),Centre for Mathematical Sciences,Departments at LTH,Faculty of Engineering, LTH (författare)
Development and validation of a new automatic algorithm for quantification of left ventricular volumes and function in gated myocardial perfusion SPECT using cardiac magnetic resonance as reference standard.
- Artikel/kapitelEngelska2011
Förlag, utgivningsår, omfång ...
- 2011-07-15
- Springer Science and Business Media LLC,2011
- electronicrdacarrier
Nummerbeteckningar
- LIBRIS-ID:oai:lup.lub.lu.se:ddf71569-f10f-4c34-aa2f-2c1083d4e241
- https://lup.lub.lu.se/record/2058644URI
- https://doi.org/10.1007/s12350-011-9427-3DOI
Kompletterande språkuppgifter
- Språk:engelska
- Sammanfattning på:engelska
Ingår i deldatabas
- SwePubSwePub
Klassifikation
Anmärkningar
- BACKGROUND: By gating image acquisition in myocardial perfusion SPECT (MPS) to ECG, left ventricular (LV) volumes and function can be determined. Several previous studies have shown that existing MPS software packages underestimate LV volumes compared to cardiac magnetic resonance (CMR). The aim of this study was therefore to develop a new LV segmentation algorithm for gated MPS using CMR as reference standard. METHODS AND RESULTS: A total of 126 patients with suspected coronary artery disease, who underwent both gated MPS and CMR were retrospectively included. The proposed LV segmentation algorithm (Segment) was trained in 26 patients, and tested in 100 patients in comparison to four commercially available MPS software packages (QGS, MyoMetrix, ECTb, and Exini) using CMR as reference standard. Mean bias ± SD between MPS and CMR was for EDV -5% ± 12%, -43% ± 8%, -40% ± 8%, -42% ± 9%, -32% ± 7%, for ESV 0% ± 17%, -41% ± 16%, -34% ± 15%, -54% ± 13%, -41% ± 10%, for EF -2% ± 13%, -1% ± 14%, -7% ± 15%, 17% ± 16%, 10% ± 17% for Segment, QGS, MyoMetrix, ECTb, and Exini, respectively, and for LVM 3% ± 18%, 33% ± 25%, 37% ± 24% for Segment, QGS, and ECTb, respectively. Correlation between MPS by Segment and CMR were for EDV R (2) = 0.89, for ESV R (2) = 0.92, for EF R (2) = 0.69, and for LVM R (2) = 0.72, with no difference compared to the correlation between the other MPS software packages and CMR (EDV R (2) = 0.86-0.92, ESV R (2) = 0.91-0.93, EF R (2) = 0.64-0.65, and LVM R (2) = 0.68-0.70). CONCLUSION: The Segment software quantifies LV volumes and EF by MPS with similar correlation and a low bias compared to other MPS software packages, using CMR as reference standard. Hence, the Segment software shows potential to provide clinically relevant volumes and functional values from MPS.
Ämnesord och genrebeteckningar
- MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Kardiologi hsv//swe
- MEDICAL AND HEALTH SCIENCES Clinical Medicine Cardiac and Cardiovascular Systems hsv//eng
- Myocardial perfusion imaging: SPECT
- left ventricular function
- gated SPECT
- magnetic resonance imaging
Biuppslag (personer, institutioner, konferenser, titlar ...)
- Hedeer, FredrikLund University,Lunds universitet,Klinisk fysiologi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Clinical Physiology (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)med-fkh (författare)
- Arévalo, CarmenLund University,Lunds universitet,Numerisk analys,Forskargrupper vid Lunds universitet,Matematik LTH,Matematikcentrum,Institutioner vid LTH,Lunds Tekniska Högskola,Numerical Analysis,Lund University Research Groups,Mathematics (Faculty of Engineering),Centre for Mathematical Sciences,Departments at LTH,Faculty of Engineering, LTH(Swepub:lu)na-car (författare)
- Carlsson, MarcusLund University,Lunds universitet,Klinisk fysiologi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Clinical Physiology (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)klin-mca (författare)
- Engblom, HenrikLund University,Lunds universitet,Klinisk fysiologi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Clinical Physiology (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)klin-hen (författare)
- Ubachs, JoeyLund University,Lunds universitet,Klinisk fysiologi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Clinical Physiology (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)med-jus (författare)
- Arheden, HåkanLund University,Lunds universitet,Klinisk fysiologi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Clinical Physiology (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)klfy-har (författare)
- Heiberg, EinarLund University,Lunds universitet,Klinisk fysiologi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Clinical Physiology (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)klin-eh0 (författare)
- Klinisk fysiologi, LundSektion V (creator_code:org_t)
Sammanhörande titlar
- Ingår i:Journal of Nuclear Cardiology: Springer Science and Business Media LLC18:5, s. 874-8851532-65511071-3581
Internetlänk
- https://portal.research.lu.se/files/2148563/2255716.pdfFULLTEXT
- http://www.ncbi.nlm.nih.gov/pubmed/21761374?dopt=AbstractFULLTEXT
- http://dx.doi.org/10.1007/s12350-011-9427-3FULLTEXT
- https://lup.lub.lu.se/search/files/2148563/2255716.pdf
- https://lup.lub.lu.se/record/2058644
- https://doi.org/10.1007/s12350-011-9427-3
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- Journal of Nuclear Cardiology (Sök värdpublikationen i LIBRIS)
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- Hedeer, Fredrik
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- Heiberg, Einar
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