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ST segment depressi...
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Johnson, Linda S BLund University,Lunds universitet,Internmedicin - epidemiologi,Forskargrupper vid Lunds universitet,Internal Medicine - Epidemiology,Lund University Research Groups
(författare)
ST segment depression on 24-hour electrocardiography predicts incident atrial fibrillation in two population-based cohorts
- Artikel/kapitelEngelska2018
Förlag, utgivningsår, omfång ...
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2017-04-10
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Oxford University Press (OUP),2018
Nummerbeteckningar
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LIBRIS-ID:oai:lup.lub.lu.se:df14757e-60f6-483a-92db-1f5805aaefab
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https://lup.lub.lu.se/record/df14757e-60f6-483a-92db-1f5805aaefabURI
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https://doi.org/10.1093/europace/eux032DOI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:137789008URI
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Språk:engelska
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Sammanfattning på:engelska
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Klassifikation
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Ämneskategori:art swepub-publicationtype
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Ämneskategori:ref swepub-contenttype
Anmärkningar
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Aims: ST-depression at 24hECG has not been studied in relation to atrial fibrillation (AF) risk. We aimed to determine whether ST-depression at 24hECG was associated with incident AF in two Swedish population-based cohorts - a sub-cohort of the Malmö Diet and Cancer study (MDCS), and the cohort 'Men born in 1914', and to determine whether 24hECG could be used to predict AF development.Methods and results: There were 378 acceptable 24hECG recordings in the MDCS (mean age 64.5 years, 43% men) and 394 acceptable recordings in 'Men born in 1914' (mean age 68.8 years). Incidence of AF was monitored using national registers of hospitalizations and outpatient visits in Sweden. Mean follow-up ± SD (cumulative incidence) was 10.4 ± 2 years (11.3%) in MDCS, and 10.9 ± 4 years (7.3%) in 'Men born in 1914'. ST-depressions were independently associated with incident AF; hazard ratio (HR) (95% CI) 2.41 (1.29-4.50, P = 0.006) and 2.28 (1.05-4.95, P = 0.038) after adjustment [age, sex, height, weight, systolic blood pressure, smoking, anti-hypertensive drugs, LDL/total cholesterol, and HOMA-IR (in MDCS)]. AF incidence was substantially lower in individuals who had neither ST-depressions or high supraventricular activity (SVA, negative predictive value 0.97 and 0.94, in MDCS and 'Men born in 1914', respectively), and similar in men and women.Conclusion: ST-depression at 24h-ECG is independently associated with incident AF, and incidence is substantially lower in individuals with neither ST-depression or high SVA. 24hECG can be used not only to diagnose AF but also to identify individuals at high and low AF risk.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Berntsson, JohnLund University,Lunds universitet,Kardiovaskulär forskning - epidemiologi,Forskargrupper vid Lunds universitet,Molecular Epidemiology and Cardiology,Cardiovascular Research - Epidemiology,Lund University Research Groups,Skåne University Hospital(Swepub:lu)med-jhb
(författare)
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Juhlin, TordLund University,Lunds universitet,Kardiologiska klinikens forskargrupp,Forskargrupper vid Lunds universitet,Cardiology Research Group,Lund University Research Groups,Skåne University Hospital(Swepub:lu)medf-tju
(författare)
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Healey, Jeff SMcMaster University
(författare)
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Juul-Möller, SteenLund University,Lunds universitet,Kardiovaskulär forskning - hypertoni,Forskargrupper vid Lunds universitet,Cardiovascular Research - Hypertension,Lund University Research Groups,Skåne University Hospital(Swepub:lu)medf-sju
(författare)
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Wollmer, PerLund University,Lunds universitet,Klinisk fysiologi och nuklearmedicin, Malmö,Forskargrupper vid Lunds universitet,Clinical Physiology and Nuclear Medicine, Malmö,Lund University Research Groups,Skåne University Hospital(Swepub:lu)klin-pwo
(författare)
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Nilsson, Peter MLund University,Lunds universitet,Internmedicin - epidemiologi,Forskargrupper vid Lunds universitet,Internal Medicine - Epidemiology,Lund University Research Groups,Skåne University Hospital(Swepub:lu)medf-pni
(författare)
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Hedblad, BoLund University,Lunds universitet,Kardiovaskulär forskning - epidemiologi,Forskargrupper vid Lunds universitet,Cardiovascular Research - Epidemiology,Lund University Research Groups,Skåne University Hospital(Swepub:lu)medf-bhe
(författare)
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Rosenqvist, MårtenKarolinska Institutet,Karolinska Institute
(författare)
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Engström, GunnarLund University,Lunds universitet,Kardiovaskulär forskning - epidemiologi,Forskargrupper vid Lunds universitet,Cardiovascular Research - Epidemiology,Lund University Research Groups,Skåne University Hospital(Swepub:lu)smi-gen
(författare)
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Internmedicin - epidemiologiForskargrupper vid Lunds universitet
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Europace: Oxford University Press (OUP)20:3, s. 429-4341532-2092
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Ingår i:EP Europace: Oxford University Press (OUP)20:3, s. 429-4341099-5129
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Europace
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Johnson, Linda S ...
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Berntsson, John
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Juhlin, Tord
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Healey, Jeff S
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Juul-Möller, Ste ...
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Wollmer, Per
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Nilsson, Peter M
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Hedblad, Bo
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Rosenqvist, Mårt ...
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Engström, Gunnar
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