Bone integration of an injectable calcium phosphate based bone substitute

• The bone formation and bone integration in calcium phosphate (CaP) and CaP with 20% calcium sulfate (CaS) were investigated. In the study, six adult, loop-eared rabbits were used and bone harvest chambers were implanted bilaterally in the proximal tibiae. It was found that the front of bone formation follows closely the front of material resorption without interposition of fibrous tissue. The results implied that a mixture of CaP and CaS can be introduced as an injectable bone graft substitute for filling bone defects.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Ortopedi (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Orthopaedics (hsv//eng)

Keyword

Bone integration

Calcium phosphate

Osteoblasts

Fibrous tissues

Publication and Content Type

kon (subject category)

ref (subject category)