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Association of Traumatic Knee Injury With Radiographic Evidence of Knee Osteoarthritis in Military Officers

Golightly, Yvonne M. (författare)
University of North Carolina
Shiue, Kristin Y. (författare)
University of North Carolina
Nocera, Maryalice (författare)
University of North Carolina
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Guermazi, Ali (författare)
Boston University
Cantrell, John (författare)
University of North Carolina
Renner, Jordan B. (författare)
University of North Carolina
Padua, Darin A. (författare)
University of North Carolina
Cameron, Kenneth L. (författare)
Svoboda, Steven J. (författare)
Jordan, Joanne M. (författare)
University of North Carolina
Loeser, Richard F. (författare)
University of North Carolina
Kraus, Virginia B. (författare)
Duke University
Lohmander, L. Stefan (författare)
Lund University,Lunds universitet,Ortopedi, Lund,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Lund OsteoArthritis Division - Nedbrytning av ledbrosk: en biologisk process som leder till artros,Forskargrupper vid Lunds universitet,Orthopaedics (Lund),Section III,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund OsteoArthritis Division - Molecular marker research group,Lund University Research Groups
Beutler, Anthony I. (författare)
Uniformed Services University of the Health Sciences
Marshall, Stephen W. (författare)
University of North Carolina
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 (creator_code:org_t)
2023-02-05
2023
Engelska.
Ingår i: Arthritis Care and Research. - : Wiley. - 2151-464X .- 2151-4658. ; 75:8, s. 1744-1751
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
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  • Objective: The association between knee injury and knee osteoarthritis (OA) is understudied relative to its importance, particularly in younger populations. This study was undertaken to examine the association of knee injury with radiographic features of knee OA in military officers, who have a physically demanding profession and high rates of knee injury. Methods: Participants were recruited in 2015–2017 from an existing program that enrolled 6,452 military officers during 2004–2009. Officers with a history of knee ligament or meniscal injuries (n = 117 via medical record review) were compared to officers with no history of knee injury (n = 143). Bilateral posteroanterior knee radiographs were obtained using a standardized fixed-flexion positioning frame. All images were read for Kellgren/Lawrence (K/L) grade, osteophyte (OST), and joint space narrowing (JSN) scores. Data were analyzed using linear-risk regression models with generalized estimating equations. Results: Injured and noninjured participants were similar (mean age 28 years, mean body mass index 25 kg/m2, ~40% female). The mean time from first knee injury to imaging among injured participants was 9.2 years. Compared with noninjured knees, greater prevalence of radiographic OA (K/L grade ≥ 2), OST (grade ≥ 1), and JSN (grade ≥ 1) was observed among injured knees, with prevalence differences of +16% (95% confidence interval [95% CI] 10%, 22%), +29% (95% CI 20%, 38%), and + 17% (95% CI 10%, 24%), respectively. Approximately 1 in 6 officers with prior knee injury progressed to radiographic OA by age 30 years. Conclusion: At the midpoint of a projected 20-year military career, officers with a history of traumatic knee injury have a markedly increased prevalence of knee radiographic OA compared to officers without injury.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Reumatologi och inflammation (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Rheumatology and Autoimmunity (hsv//eng)

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