id:"swepub:oai:lup.lub.lu.se:e02eb19a-bed8-43d9-92f5-c0608a300e30"
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- Kendler, Kenneth S.Virginia Commonwealth University (författare)
Geographical proximity and the transmission of drug abuse among siblings : Evaluating a contagion model in a Swedish National Sample
- Artikel/kapitelEngelska2020
Förlag, utgivningsår, omfång ...
- 2020
- 9 s.
Nummerbeteckningar
- LIBRIS-ID:oai:lup.lub.lu.se:e02eb19a-bed8-43d9-92f5-c0608a300e30
- https://lup.lub.lu.se/record/e02eb19a-bed8-43d9-92f5-c0608a300e30URI
- https://doi.org/10.1017/S2045796019000453DOI
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- Språk:engelska
- Sammanfattning på:engelska
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Anmärkningar
- AimsCan drug abuse (DA) be transmitted psychologically between adult siblings consistent with a social contagion model?MethodsWe followed Swedish sibling pairs born in 1932-1990 until one of them, sibling1 (S1), had a first DA registration. We then examined, using Cox regression, the hazard rate for a first registration for DA in sibling2 (S2) within 3 years of a first DA registration in S1 as a function of their geographical proximity. We examined 153 294 informative pairs. To control for familial confounding, we repeated these analyses in sibships containing multiple pairs, comparing risk in different siblings with their proximity to S1. DA was recorded in medical, criminal or pharmacy registries.ResultsThe best-fit model predicted risk for DA in S2 as a function of the log of kilometres between S1 and S2 with parameter estimates (±95% confidence intervals) of 0.94 (0.92; 0.95). Prediction of DA included effects of cohabitation and an interaction of proximity and time since S1 registration with stronger effects of proximity early in the follow-up period. Proximity effects were stronger for smaller S1-S2 age differences and for same-v. opposite-sex pairs. Sibship analyses confirmed sibling-pair results.ConclusionsConsistent with a social contagion model, the probability of transmission of a first registration for DA in sibling pairs is related to their geographical proximity and similarity in age and sex. Such effects for DA are time-dependent and include cohabitation effects. These results illustrate the complexity of the familial aggregation of DA and support efforts to reduce their contagious spread within families in adulthood.
Ämnesord och genrebeteckningar
- MEDICIN OCH HÄLSOVETENSKAP Hälsovetenskap Beroendelära hsv//swe
- MEDICAL AND HEALTH SCIENCES Health Sciences Substance Abuse hsv//eng
- Drug abuse
- epidemiology
- social contagion
- spatial clustering
Biuppslag (personer, institutioner, konferenser, titlar ...)
- Ohlsson, HenrikCenter for Primary Health Care Research(Swepub:lu)med-heo (författare)
- Edwards, Alexis C.Virginia Commonwealth University(Swepub:lu)al7546ed (författare)
- Sundquist, JanLund University,Lunds universitet,Allmänmedicin och klinisk epidemiologi,Forskargrupper vid Lunds universitet,Family Medicine and Clinical Epidemiology,Lund University Research Groups,Shimane University,Icahn School of Medicine at Mount Sinai(Swepub:lu)med-jsu (författare)
- Sundquist, KristinaLund University,Lunds universitet,Allmänmedicin, kardiovaskulär epidemiologi och levnadsvanor,Forskargrupper vid Lunds universitet,Family Medicine, Cardiovascular Epidemiology and Lifestyle,Lund University Research Groups,Shimane University,Icahn School of Medicine at Mount Sinai(Swepub:lu)med-ksq (författare)
- Virginia Commonwealth UniversityCenter for Primary Health Care Research (creator_code:org_t)
Sammanhörande titlar
- Ingår i:Epidemiology and Psychiatric Sciences292045-7960
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