Practical and physiological aspects of breath alcohol analysis

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Grubb, DavidLund University,Lunds universitet,Anestesiologi och intensivvård,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Anesthesiology and Intensive Care,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine (författare)

Practical and physiological aspects of breath alcohol analysis

BokEngelska2013

Förlag, utgivningsår, omfång ...

2013
133 s.

Nummerbeteckningar

LIBRIS-ID:oai:lup.lub.lu.se:e03f4e60-7f38-4379-a02d-53019db34348
ISBN:9789187189968
https://lup.lub.lu.se/record/3513153URI

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Språk:engelska
Sammanfattning på:engelska

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Ämneskategori:vet swepub-contenttype

Serie

Lund University Faculty of Medicine Doctoral Dissertation Series,1652-8220

Anmärkningar

Breath alcohol analysis constitutes sufficient material for the prosecution of drunk driving without the need for blood analysis. However, the prevailing method used for breath analysis lacks standardization of several physiological variables that cause a variation of the breath alcohol concentration (BrAC). In this thesis, a novel analyzer which standardizes the BrAC to the water vapour concentration was used to investigate different aspects of breath analysis. In study I the BrAC-profile and elimination rate of mouth alcohol (MA), a potential source of error, was investigated. It was concluded that the BrAC-profile is an unreliable means to detect MA and that the elimination rate is independent of blood alcohol. In study II the precision of breath and blood analysis was compared and the relationship between breath and blood alcohol concentrations was investigated. It was shown that the precision of breath and blood analysis was equally good and that there was a stable relationship between the breath and blood alcohol concentrations from 30 minutes and onward after alcohol administration. In study III the mechanisms of alcohol exchange within the lungs were investigated. The results implied that there is a significant exchange of alcohol with the conducting airways and that this exchange causes a relatively low BrAC in the early absorption phase. In study IV the analytical performance of BrAC-measurements by standardization to water vapour was determined. The method complies with standards for evidential breath testing and allows analysis without mouth piece with a nearly intact accuracy and precision.

Ämnesord och genrebeteckningar

MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Anestesi och intensivvård hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Anesthesiology and Intensive Care hsv//eng
Breath alcohol analysis
Mouth alcohol
Analytical performance
Blood breath ratio
Alcohol exchange
Standardization
Contact free analysis.

Biuppslag (personer, institutioner, konferenser, titlar ...)

Anestesiologi och intensivvårdSektion II (creator_code:org_t)

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https://lup.lub.lu.se/record/3513153

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Av författaren/redakt...: Grubb, David

Om ämnet

MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Anestesi och int ...

Delar i serien: Lund University ...

Av lärosätet: Lunds universitet

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