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Inter-institutional analysis of the outcome after postcardiotomy veno-arterial extracorporeal membrane oxygenation
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- Biancari, Fausto (author)
- University of Helsinki,Helsinki University Central Hospital
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- Mäkikallio, Timo (author)
- University of Helsinki
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- Loforte, Antonio (author)
- St. Orsola-Malpighi University Hospital
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Kaserer, Alexander (author)
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- Ruggieri, Vito G. (author)
- Robert Debré University Hospital,University Hospital Of Trieste
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- Cho, Sung Min (author)
- Johns Hopkins University School of Medicine
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- Kang, Jin Kook (author)
- Johns Hopkins University School of Medicine
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- Dalén, Magnus (author)
- Karolinska Institutet,Karolinska University Hospital
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- Welp, Henryk (author)
- University Hospital Münster
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- Jónsson, Kristján (author)
- Sahlgrenska University Hospital
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- Ragnarsson, Sigurdur (author)
- Lund University,Lunds universitet,Thoraxkirurgi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Minimalinvasiv hjärtkirurgi vid hjärtklaffsjukdom,Forskargrupper vid Lunds universitet,Blödningsrubbningar och akut typ-A dissektion,Heparinbindande protein inom thoraxkirurgi,Thoracic Surgery,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Minimal invasive cardiac surgery in valvular heart disease,Lund University Research Groups,Bleeding disorders and acute typ-A dissection,Heparin bindning protein in cardiothoracic surgery
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- Hernández Pérez, Francisco J. (author)
- University Hospital Puerta de Hierro
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- Gatti, Giuseppe (author)
- University Hospital Of Trieste
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- Alkhamees, Khalid (author)
- Prince Sultan Cardiac Center
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- Fiore, Antonio (author)
- Henri Mondor Hospital
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- Lechiancole, Andrea (author)
- University Hospital of Udine
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Rosato, Stefano (author)
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- Spadaccio, Cristiano (author)
- Mayo Clinic Minnesota
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- Pettinari, Matteo (author)
- Hospital Oost-Limburg
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- Perrotti, Andrea (author)
- University Hospital Jean Minjoz
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Sahli, Sebastian D. (author)
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- L’Acqua, Camilla (author)
- Istituto Nazionale dei Tumori,Centro Cardiologico Monzino
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- Arafat, Amr A. (author)
- Tanta University,Prince Sultan Cardiac Center
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- Albabtain, Monirah A. (author)
- Prince Sultan Cardiac Center
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- AlBarak, Mohammed M. (author)
- Prince Sultan Cardiac Center
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- Laimoud, Mohamed (author)
- Cairo University
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- Djordjevic, Ilija (author)
- University Hospital of Cologne
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- Krasivskyi, Ihor (author)
- University Hospital of Cologne
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- Samalavicius, Robertas (author)
- Vilnius University
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- Jankuviene, Agne (author)
- Vilnius University
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- Alonso-Fernandez-Gatta, Marta (author)
- University Hospital of Salamanca,Carlos III Health Institute
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- Wilhelm, Markus J. (author)
- University Hospital of Zurich
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- Juvonen, Tatu (author)
- Helsinki University Central Hospital,University of Oulu
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- Mariscalco, Giovanni (author)
- Glenfield Hospital
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(creator_code:org_t)
- 2024
- 2024
- English 10 s.
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In: International Journal of Artificial Organs. - 0391-3988 .- 1724-6040. ; 47:1, s. 25-34
- Related links:
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http://dx.doi.org/10...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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Abstract
Subject headings
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- Introduction: Patients requiring postcardiotomy veno-arterial extracorporeal membrane oxygenation (V-A-ECMO) have a high risk of early mortality. In this analysis, we evaluated whether any interinstitutional difference exists in the results of postcardiotomy V-A-ECMO. Methods: Studies on postcardiotomy V-A-ECMO were identified through a systematic review for individual patient data (IPD) meta-analysis. Analysis of interinstitutional results was performed using direct standardization, estimation of observed/expected in-hospital mortality ratio and propensity score matching. Results: Systematic review of the literature yielded 31 studies. Data from 10 studies on 1269 patients treated at 25 hospitals were available for the present analysis. In-hospital mortality was 66.7%. The relative risk of in-hospital mortality was significantly higher in six hospitals. Observed versus expected in-hospital mortality ratio showed that four hospitals were outliers with significantly increased mortality rates, and one hospital had significantly lower in-hospital mortality rate. Participating hospitals were classified as underperforming and overperforming hospitals if their observed/expected in-hospital mortality was higher or lower than 1.0, respectively. Among 395 propensity score matched pairs, the overperforming hospitals had significantly lower in-hospital mortality (60.3% vs 71.4%, p = 0.001) than underperforming hospitals. Low annual volume of postcardiotomy V-A-ECMO tended to be predictive of poor outcome only when adjusted for patients’ risk profile. Conclusions: In-hospital mortality after postcardiotomy V-A-ECMO differed significantly between participating hospitals. These findings suggest that in many centers there is room for improvement of the results of postcardiotomy V-A-ECMO.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Keyword
- ECMO
- Extracorporeal membrane oxygenation
- postcardiotomy
- volume
Publication and Content Type
- art (subject category)
- ref (subject category)
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- By the author/editor
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Biancari, Fausto
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Mäkikallio, Timo
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Loforte, Antonio
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Kaserer, Alexand ...
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Ruggieri, Vito G ...
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Cho, Sung Min
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show more...
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Kang, Jin Kook
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Dalén, Magnus
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Welp, Henryk
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Jónsson, Kristjá ...
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Ragnarsson, Sigu ...
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Hernández Pérez, ...
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Gatti, Giuseppe
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Alkhamees, Khali ...
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Fiore, Antonio
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Lechiancole, And ...
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Rosato, Stefano
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Spadaccio, Crist ...
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Pettinari, Matte ...
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Perrotti, Andrea
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Sahli, Sebastian ...
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L’Acqua, Camilla
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Arafat, Amr A.
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Albabtain, Monir ...
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AlBarak, Mohamme ...
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Laimoud, Mohamed
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Djordjevic, Ilij ...
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Krasivskyi, Ihor
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Samalavicius, Ro ...
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Jankuviene, Agne
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Alonso-Fernandez ...
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Wilhelm, Markus ...
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Juvonen, Tatu
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Mariscalco, Giov ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Cardiac and Card ...
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International Jo ...
- By the university
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Lund University
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Karolinska Institutet