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Fatigue trajectorie...
Fatigue trajectories during pediatric ALL therapy are associated with fatigue after treatment: a national longitudinal cohort study
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- Irestorm, Elin (författare)
- Lund University,Lunds universitet,Pediatrisk onkologi,Forskargrupper vid Lunds universitet,Childhood Cancer Research Unit,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Pediatric Oncology,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Princess Maxima Center for Pediatric Oncology/Hematology
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- Steur, Lindsay M.H (författare)
- Princess Maxima Center for Pediatric Oncology/Hematology
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- Kaspers, Gertjan J. L. (författare)
- Princess Maxima Center for Pediatric Oncology/Hematology
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- Van Eijkelenburg, Natasha K.A. (författare)
- Princess Maxima Center for Pediatric Oncology/Hematology
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- van der Sluis, Inge Margriet (författare)
- Princess Maxima Center for Pediatric Oncology/Hematology
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- Dors, Natasja (författare)
- Princess Maxima Center for Pediatric Oncology/Hematology
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- van den Bos, Cor (författare)
- Academic Medical Center of University of Amsterdam (AMC)
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- Tissing, Wim J E (författare)
- University of Groningen
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- Grootenhuis, Martha A. (författare)
- Princess Maxima Center for Pediatric Oncology/Hematology
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- van Litsenburg, Raphaele R.L. (författare)
- Princess Maxima Center for Pediatric Oncology/Hematology
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(creator_code:org_t)
- 2022-12-13
- 2023
- Engelska.
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Ingår i: Supportive Care in Cancer. - : Springer Science and Business Media LLC. - 1433-7339 .- 0941-4355. ; 31:1, s. 1-9
- Relaterad länk:
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http://dx.doi.org/10... (free)
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Objective: Fatigue is one of the most prevalent and distressing symptoms reported by survivors of childhood cancer. There is currently a lack of longitudinal studies on cancer-related fatigue, and especially on the relationship between the course of fatigue during treatment and fatigue at follow-up. The purpose of the current study was therefore to investigate if the course of fatigue during treatment, treatment intensity, serious adverse events, sex, or age at diagnosis are associated with cancer-related fatigue after treatment.Methods: Participants were 92 children and adolescents diagnosed with acute lymphoblastic leukemia (mean age at diagnosis was 6.26 years). Fatigue was measured with PedsQL multidimensional fatigue scale proxy reports 5 months after diagnosis,12 months after diagnosis, 24 months after diagnosis, and at follow-up 12 months after end of treatment. The effect of patient and treatment characteristics on fatigue reported at follow-up was tested through logistic regression analyses.Results: The course of fatigue during treatment signifcantly predicted fatigue reported at follow-up for general fatigue (p=.038, OR=9.20), sleep/rest fatigue (p=.011, OR=15.48), and cognitive fatigue (pConclusions The fndings demonstrate that fatigue reported during treatment can predict fatigue at follow-up. These results stress the need for longitudinal assessments. Healthcare professionals need to be aware that pediatric patients who are fatigued during treatment need to receive additional attention and timely interventions since cancer-related fatigue will not resolve by itself in the frst year after end of treatment.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Pediatrik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Pediatrics (hsv//eng)
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